Grant: Research Tools and Instruments - Category 1 (<$150,000)
York University
$13,063.00
Protein Purification Platform Upgrade for Structural Biology Research
FY 2011-12
Summary
My laboratory's primary focus is the structural determination of protein complexes by NMR spectroscopy and X-ray crystallography. This research is funded by a 2011-2016 NSERC Discovery Grant and a 2011-2014 NSERC Discovery Accelerator Award. One of the most integral components of the workflow in this research environment is efficient and reproducible protein purification using a combination of manual and automated chromatography instruments. The chromatography equipment in the laboratory was purchased in 2001 with startup funds and a CFI New Opportunities award. Six months ago, the fraction collector robot on the only automated (AKTA FPLC) chromatography system failed. This proposal represents a request for funds to replace the fraction collector as well as a few minor maintenance items such as an ultraviolet lamp for the detector.
Program
Research Tools and Instruments - Category 1 (<$150,000)
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
422543-2012
Name nom
Donaldson, Logan
Department département
Biology
Organization id
38
Institution établissement
York University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2011
Competition year année de concours
2012
Award amount
13063
Program id
EQPEQ
Program nane en
Research Tools and Instruments - Category 1 (<$150,000)
Program name fr
Outils et instruments de recherche - catégorie 1 (<150 000$)
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1501
Committee name en
Genes, Cells and Molecules
Committee name fr
Gènes, cellules et molécules
Area of application code
1101
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Human health (including medically-related psychological research)
Area of application fr
Santé publique (y compris recherche psychologique liée à la médecine)
Research subject code
5403
Research subject group en
Biochemistry
Research subject group fr
Biochimie
Research subject en
Proteins and peptides, amino acids
Research subject fr
Protéines et peptides, acides aminés
Partie
1
Nb partie
1
Application title
Protein Purification Platform Upgrade for Structural Biology Research
Keyword
NSERC
Application summary
My laboratory's primary focus is the structural determination of protein complexes by NMR spectroscopy and X-ray crystallography. This research is funded by a 2011-2016 NSERC Discovery Grant and a 2011-2014 NSERC Discovery Accelerator Award. One of the most integral components of the workflow in this research environment is efficient and reproducible protein purification using a combination of manual and automated chromatography instruments. The chromatography equipment in the laboratory was purchased in 2001 with startup funds and a CFI New Opportunities award. Six months ago, the fraction collector robot on the only automated (AKTA FPLC) chromatography system failed. This proposal represents a request for funds to replace the fraction collector as well as a few minor maintenance items such as an ultraviolet lamp for the detector.