Grant: Canada Research Chairs
Concordia University
$200,000.00
Microbial Genomics
FY 2023-24
Summary
We will establish the transcriptional networks of the human fungal pathogen Candida albicans, and
compare them with those in Saccharomyces cerevisiae. We will identify those circuits that are
unique to each organism, those circuits that are common to both organisms, and finally those
circuits that have rewired between the organisms and thus control distinct processes in the two
fungi. While investigations of the transcriptional circuitry in the model yeast S. cerevisiae have
provided fundamental insights into cell function, our work will establish which characteristics are
fundamental, and which are idiosyncratic to the model under investigation.
Program
Canada Research Chairs
Recipient
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
CRC-2019-00257
Name nom
Whiteway, Malcolm
Department département
Head Office
Organization id
70
Institution établissement
Concordia University
Province en
Québec
Province fr
Québec
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2023
Competition year année de concours
2019
Award amount
200000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
10000
Research subject group en
The field of research available
Research subject group fr
The field of research available
Research subject en
Le domaine de recherche disponible
Research subject fr
Le domaine de recherche disponible
Field of research list codes
RDF10606
Field of research list names en
Genetics
Field of research list names fr
Génétique
Application title
Microbial Genomics
Keyword
transcription profiling
regulatory networks
Candida ; albicans
RNAseq
rewiring
transcription factor activation
Application summary
We will establish the transcriptional networks of the human fungal pathogen Candida albicans, and
compare them with those in Saccharomyces cerevisiae. We will identify those circuits that are
unique to each organism, those circuits that are common to both organisms, and finally those
circuits that have rewired between the organisms and thus control distinct processes in the two
fungi. While investigations of the transcriptional circuitry in the model yeast S. cerevisiae have
provided fundamental insights into cell function, our work will establish which characteristics are
fundamental, and which are idiosyncratic to the model under investigation.
