Grant: Engage Grants Program
Cape Breton University
$25,000.00
Feasibility test of lateral flow asssays for type 1 plasminogen activator inhibitor
FY 2016-17
Summary
As one of the primary regulators of the fibrinolytic system in human beings, plasminogen activator inhibitortype 1 (PAI-1) has been involved in various thrombotic disorders. In the medical industry associated withthrombosis, there is a need for rapid and simple PAI-1 detection methodologies. Lateral Flow Immunoassay(LFA), a fast and single-step analytical platform, has been widely adopted for various point-of-careapplications, such as home-use pregnancy test strips. Thus, it is meaningful to study the adaptability of the LFAtechnology for PAI-1 detection, especially for BioMedica Diagnostics Incorporation (BMD), which is anindustrial leader in the diagnosis market for thrombosis and haemostasis. In this project, a preliminary test ofthe technical parameters and performance of the LFA for PAI-1 will be conducted. The results will becompared to the established ELISA platform for validation and commercial feasibility evaluation.
Program
Engage Grants Program
Recipient
Location
Nova Scotia, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
507299-2016
Name nom
Zhang, Xu(Shine)
Department département
Verschuren Centre for Sustainability in Energy and the Environment
Organization id
84
Institution établissement
Cape Breton University
Province en
Nova Scotia
Province fr
Nouvelle-Écosse
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2016
Competition year année de concours
2016
Award amount
25000
Program id
EGP
Program name en
Engage Grants Program
Program name fr
Programme de subventions d'engagement partenariat
Group en
Research partnerships programs
Group fr
Programmes de partenariat
Committee code
1551
Committee name en
Atlantic Internal Decision Committee
Committee name fr
Comité de décision interne pour l'Atlantique
Area of application code
1102
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Biomedical engineering
Area of application fr
Génie biomédical
Research subject code
3504
Research subject group en
Analytical chemistry
Research subject group fr
Chimie analytique
Research subject en
Bioanalytical chemistry
Research subject fr
Chimie bioanalytique
Partie
1
Nb partie
1
Application title
Feasibility test of lateral flow asssays for type 1 plasminogen activator inhibitor
Keyword
NSERC
Application summary
As one of the primary regulators of the fibrinolytic system in human beings, plasminogen activator inhibitortype 1 (PAI-1) has been involved in various thrombotic disorders. In the medical industry associated withthrombosis, there is a need for rapid and simple PAI-1 detection methodologies. Lateral Flow Immunoassay(LFA), a fast and single-step analytical platform, has been widely adopted for various point-of-careapplications, such as home-use pregnancy test strips. Thus, it is meaningful to study the adaptability of the LFAtechnology for PAI-1 detection, especially for BioMedica Diagnostics Incorporation (BMD), which is anindustrial leader in the diagnosis market for thrombosis and haemostasis. In this project, a preliminary test ofthe technical parameters and performance of the LFA for PAI-1 will be conducted. The results will becompared to the established ELISA platform for validation and commercial feasibility evaluation.
