Grant: Travel Awards - Institute Community Support
University of Toronto
$1,000.00
Analysis of nanoparticle tumour targeting
FY 2016-17
Summary
Nanoparticle based diagnosis and treatment of cancer is a promising but challenging concept. Upon surveying manuscripts published from 2005 to 2015, we found that only 0.7% of the injected nanoparticle dose actually reach the targeted solid tumour tissue in preclinical animal models. In other words, the delivery of nanoparticles to tumours is limited and only 7 out of 1,000 administered nanoparticles accumulate at the target site. My presentation will explore the potential causes of the poor delivery efficiency and discuss the impact of these results on the clinical translation of nanomedicines for human cancer care.
Department
Program
Travel Awards - Institute Community Support
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
364563
Name
Wilhelm Stefan
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Institute of Cancer Research
Projecttitle
Analysis of nanoparticle tumour targeting
Programtype2
Undefined
Orgnameinp2
University of Toronto
Cihramount2
$1,000
Cihrequipment2
$0
Programname2
Travel Awards - Institute Community Support
Keyworddelim
Biodistribution; Cancer Treatment; Nanomedicine; Nanoparticles; Tumour Targeting
Abstract
Nanoparticle based diagnosis and treatment of cancer is a promising but challenging concept. Upon surveying manuscripts published from 2005 to 2015, we found that only 0.7% of the injected nanoparticle dose actually reach the targeted solid tumour tissue in preclinical animal models. In other words, the delivery of nanoparticles to tumours is limited and only 7 out of 1,000 administered nanoparticles accumulate at the target site. My presentation will explore the potential causes of the poor delivery efficiency and discuss the impact of these results on the clinical translation of nanomedicines for human cancer care.
Competitiondate
201701
Approvedterm2
1 yr 0 mth
Pinamesdelim
Wilhelm, Stefan
Approvedterm
1 an 0 mois
Cihrcontribution2
Inst of Cancer Research~ $1,000~ $0~
