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Grant: Project Grant

University of Alberta

$906,525.00

133/135La radiopharmaceuticals: Novel radiotheragnostics for PET imaging and Meitner-Auger electron (MAE) therapy in nuclear medicine

FY 2024-25

Summary
The proposed health research project describes the testing of a novel radionuclide pair for better diagnosis and therapy of cancer. The project will mainly study the therapeutic effect of a special type of electrons emitted by one of the radionuclides. The electrons travel only a short distance in tissue, killing cancer cells efficiently while sparing the surrounding healthy tissue. We will incorporate the radionuclide into molecules that bind specifically to cancer cells. The novel radionuclide pair will help to find and kill cancer cells in the body. A task of this magnitude can only be achieved with the help of a strong research team. We have assembled an expert research team of chemists, physicists, cancer researchers, and physicians to accomplish this multidisciplinary research project. If successful, the project will help to introduce new technology into the clinic to enhance patient care and improve outcomes.
Program
Project Grant
Location
Alberta, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
509288
Name
Wuest Frank
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Pharmaceutical Sciences
Projecttitle
133/135La radiopharmaceuticals: Novel radiotheragnostics for PET imaging and Meitner-Auger electron (MAE) therapy in nuclear medicine
Programtype2
Operating Grants
Orgnameinp2
University of Alberta
Cihramount2
$906,525
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Meitner-Auger Electrons; Pet Imaging; Radiation Biology; Radiopharmaceuticals; Targeted Radiotherapy; Theragnostics
Abstract
The proposed health research project describes the testing of a novel radionuclide pair for better diagnosis and therapy of cancer. The project will mainly study the therapeutic effect of a special type of electrons emitted by one of the radionuclides. The electrons travel only a short distance in tissue, killing cancer cells efficiently while sparing the surrounding healthy tissue. We will incorporate the radionuclide into molecules that bind specifically to cancer cells. The novel radionuclide pair will help to find and kill cancer cells in the body. A task of this magnitude can only be achieved with the help of a strong research team. We have assembled an expert research team of chemists, physicists, cancer researchers, and physicians to accomplish this multidisciplinary research project. If successful, the project will help to introduce new technology into the clinic to enhance patient care and improve outcomes.
Competitiondate
202409
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Wuest, Frank
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $906,525~ $0~
University of Alberta - $906,525 Grant (2024-25) | Canada Spends