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Grant: Research Tools and Instruments

Carleton University

$150,000.00

Time-gated Raman spectroscopy for a more sensitive and reliable determination of analytes in the field of agri-food, biology and engineering

FY 2023-24

Summary
We request funds to procure a portable fiber-based, time-gated Raman (PF-TG-Raman) spectrometer to develop rapid, sensitive and reliable methods to analyze a variety of analytes, e.g., chemical hazards in agri-food, food adulterants, plastics, and biomarkers for diseases. Conventional Raman spectrometers suffer from the strong fluorescence background which impairs its sensitivity and reliability for analyzing auto-fluorescent (e.g., agri-food and biological samples) and coloured samples (e.g., plastics). In comparison, TG-Raman spectrometers avoid the fluorescent signals from the source by taking advantage of the difference in lifetime between Raman scattering and fluorescence, improving the sensitivity of Raman spectroscopic based analysis and broadening the application of Raman spectroscopy to samples with strong fluorescent signals. The effective fluorescence removal of TG-Raman spectrometer is achieved by utilizing a picosecond time-frame pulsed laser and a rapid, sensitive detector which only allow the signals of Raman scattering to be collected. There is currently no instrument with similar capabilities available at Carleton University. This PF-TG-Raman spectrometer is in an urgent need by researchers (i.e., 4 applicants and 4 confirmed users) across five academic units (i.e., Chemistry, Physics, Biology, Biochemistry, Systems & Computer Engineering, and Mechanical & Aerospace Engineering) that spans two Faculties (i.e., Science, and Engineering & Design) at Carleton University. Specific research themes to be supported by this advanced PF-TG-Raman spectrometer include: 1) identification of plastics and microplastics in food, environment and solid waste; 2) food authentication; 3) detection and quantification of chemical hazards in foods and environment; and 4) medical diagnostics. In additional to maintaining established research projects (e.g., NSERC DG), the requested instrument will also create new research collaborations and funding opportunities (e.g., NSERC Alliance) in the aforementioned research areas and beyond. Moreover, over 100 HQP in the applicants' and confirmed users' groups will acquire hands-on experience on the PF-TG-Raman spectrometer over the next five years, preparing them to be more competitive in the job market within and beyond academia. The requested instrument will be a critical workhorse for the next decade and will add great value to Carleton and its employees via HQP training and by promoting research excellence in several fields of science and engineering.
Program
Research Tools and Instruments
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data

As published

Application id
RTI-2024-00300
Name nom
Hu, Yaxi
Department département
Chemistry
Organization id
23
Institution établissement
Carleton University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2023
Competition year année de concours
2024
Award amount
150000
Program id
RTI
Program name en
Research Tools and Instruments
Program name fr
Outils et instruments de recherche
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
1602
Committee name en
Biological Systems and Functions (RTI)
Committee name fr
Systèmes et fonctions biologiques (OIR)
Area of application code
506
Area of application group en
Manufacturing processes and products
Area of application group fr
Procédés et produits industriels
Area of application en
Agricultural chemicals (fertilizers, herbicides, pesticides)
Area of application fr
Produits chimiques agricoles (engrais, pesticides, herbicides)
Research subject code
3505
Research subject group en
Analytical chemistry
Research subject group fr
Analytical spectroscopy
Research subject en
Chimie analytique
Research subject fr
Spectroscopie analytique
Application title
Time-gated Raman spectroscopy for a more sensitive and reliable determination of analytes in the field of agri-food, biology and engineering
Keyword
Food authentication; Food safety analysis; Non-destructive analysis; Plastic and microplastic sorting; Portable Raman spectrometer; Sensitive Biomarket analysis; Surface enhanced Raman spectroscopy; Time-gated Raman spectroscopy
Application summary
We request funds to procure a portable fiber-based, time-gated Raman (PF-TG-Raman) spectrometer to develop rapid, sensitive and reliable methods to analyze a variety of analytes, e.g., chemical hazards in agri-food, food adulterants, plastics, and biomarkers for diseases. Conventional Raman spectrometers suffer from the strong fluorescence background which impairs its sensitivity and reliability for analyzing auto-fluorescent (e.g., agri-food and biological samples) and coloured samples (e.g., plastics). In comparison, TG-Raman spectrometers avoid the fluorescent signals from the source by taking advantage of the difference in lifetime between Raman scattering and fluorescence, improving the sensitivity of Raman spectroscopic based analysis and broadening the application of Raman spectroscopy to samples with strong fluorescent signals. The effective fluorescence removal of TG-Raman spectrometer is achieved by utilizing a picosecond time-frame pulsed laser and a rapid, sensitive detector which only allow the signals of Raman scattering to be collected. There is currently no instrument with similar capabilities available at Carleton University. This PF-TG-Raman spectrometer is in an urgent need by researchers (i.e., 4 applicants and 4 confirmed users) across five academic units (i.e., Chemistry, Physics, Biology, Biochemistry, Systems & Computer Engineering, and Mechanical & Aerospace Engineering) that spans two Faculties (i.e., Science, and Engineering & Design) at Carleton University. Specific research themes to be supported by this advanced PF-TG-Raman spectrometer include: 1) identification of plastics and microplastics in food, environment and solid waste; 2) food authentication; 3) detection and quantification of chemical hazards in foods and environment; and 4) medical diagnostics. In additional to maintaining established research projects (e.g., NSERC DG), the requested instrument will also create new research collaborations and funding opportunities (e.g., NSERC Alliance) in the aforementioned research areas and beyond. Moreover, over 100 HQP in the applicants' and confirmed users' groups will acquire hands-on experience on the PF-TG-Raman spectrometer over the next five years, preparing them to be more competitive in the job market within and beyond academia. The requested instrument will be a critical workhorse for the next decade and will add great value to Carleton and its employees via HQP training and by promoting research excellence in several fields of science and engineering.
Carleton University - $150,000 Grant (2023-24) | Canada Spends