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Grant: Collaborative Science, Technology and Innovation Program – Ideation Fund

Simon Fraser University

$12,500.00

Exploiting Collateral Sensitivity to Win the War Against Antimicrobial Resistance

FY 2019-20 · 2020-03-25

Summary
Many antibiotics are derived from natural products, small molecules made by organisms in the environment. In this project, high-throughput screening and chemical analysis will be used to isolate and identify novel natural products with unique activities against drug-resistant strains of E. coli. Using this approach, it is anticipated that a new classes of bioactive compounds will be identified that could form the foundation for future drug development.
Program
Collaborative Science, Technology and Innovation Program – Ideation Fund
Location
BURNABY, British Columbia, Canada
Recipient Type
Academia
Business Number
118520725
Type
Grant
Source
Proactive Disclosure - Grants and Contributions

As published

Additional Information
This agreement has been amended 1 time(s). The end date of this agreements has been modified by 182 days. The total amended value is 29,900 dollars.
Additional Information (French)
Cet accord a été modifié 1 fois La date de fin du présent accord a été changé de 182 jours. La valeur totale des modifications est de 29 900 dollars.
Agreement End Date
2021-03-31
Agreement Number
946583
Agreement Start Date
2020-03-25
Agreement Title
Exploiting Collateral Sensitivity to Win the War Against Antimicrobial Resistance
Agreement Title (French)
Recours à la sensibilité collatérale pour vaincre l’antibiorésistance
Agreement Type
Grant
Agreement Value
$12,500.00
Amendment Number
0
Description
Many antibiotics are derived from natural products, small molecules made by organisms in the environment. In this project, high-throughput screening and chemical analysis will be used to isolate and identify novel natural products with unique activities against drug-resistant strains of E. coli. Using this approach, it is anticipated that a new classes of bioactive compounds will be identified that could form the foundation for future drug development.
Description (French)
Beaucoup d’antibiotiques dérivent de produits naturels, de petites molécules synthétisées par différents organismes dans l’environnement. On isolera et découvrira de nouveaux produits naturels qui agiront de manière particulière sur les souches antibiorésistantes d’E. coli par sélection à fort débit et analyse chimique. Cette approche devrait aboutir à la découverte de nouveaux composés bioactifs à partir desquels on créera les médicaments de demain.
Expected Results
In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators.
Expected Results (French)
À court terme, les résultats prévus sont des collaborations renforcées dans l’ensemble de l’industrie, du milieu universitaire et du gouvernement afin d’appuyer l’excellence en recherche. À moyen terme, les résultats prévus sont le développement de technologies potentiellement perturbatrices avec des collaborateurs.
Federal Riding
Burnaby North–Seymour
Federal Riding (French)
Burnaby-Nord–Seymour
Federal Riding Number
59002
NAICS Code
541710
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Collaborative Science, Technology and Innovation Program – Ideation Fund
Program Name (French)
Programme de collaboration en science, en technologie et en innovation – Fonds d’idéation
Program Purpose
The Ideation Fund is intended to encourage, test and validate transformative research ideas generated by teams of NRC scientific personnel and external collaborators with complementary capabilities, acting as a demonstration phase for a continually-evolving suite of research and development (R&D) deliverables at the NRC. The fund supports exploratory research through two mechanisms: the New Beginnings Initiative and the Small Teams Initiative.
Program Purpose (French)
Le Fonds d’idéation vise à encourager, à mettre à l’essai et à valider les idées de recherche transformatrice des équipes scientifiques du CNRC et des collaborateurs externes dotés de capacités complémentaires. Il servira ainsi de plateforme de démonstration d’une série de produits livrables en matière de recherche-développement (R-D) en constante évolution au CNRC. Le Fonds appuie la recherche exploratoire au moyen de deux mécanismes : l’Initiative « Nouveaux débuts » et l’Initiative « Petites équipes ».
Recipient Business Number
118520725
Recipient City
BURNABY
Recipient Country
CA
Recipient Legal Name
Simon Fraser University
Recipient Operating Name
Simon Fraser University
Recipient Postal Code
V5A 1S6
Recipient Province or Territory
BC
Recipient Type
S
Reference Number
172-2019-2020-Q4-946583