Grant: Operating Grant - PA: HIV/AIDS Res Initiative - Hlth Svs/Population Hlth Stream
University of British Columbia
$293,606.00
Development of an observational database of clinical characteristics and outcomes among HIV+ adults and children in Uganda.
FY 2008-09
Summary
Determining the best clinical care for HIV/AIDS is of utmost importance in sub-Saharan Africa. Evaluating the natural progression of HIV/AIDS and also co-infections can determine important public health outcomes for planning and intervening in the epidemic. We propose to work with the oldest and largest community-based AIDS organization in Africa, The AIDS Support Organization (TASO), to develop a database suitable for operational research and clinical research to determine patient outcomes, programme implementation, and predict future clinical outcomes. This database currently has accurate data on more than 24,000 patients receiving antiretroviral therapy and a further 80,000 patients receiving pre-antiretroviral clinical care. We now must organize this database for the purpose of large-scale research. We aim to determine the following specific research questions: 1) What CD4 T-cell threshold should be used for treatment initiation? 2) What is the expected duration of survival for patients receiving antiretroviral therapy in Uganda? This will be the largest observational study for HIV/AIDS in the developing world.
Department
Program
Operating Grant - PA: HIV/AIDS Res Initiative - Hlth Svs/Population Hlth Stream
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
186773
Name
Mills Edward J
Region
British Columbia
Country
Canada
Orgtype
Research Institution; Institution Paid
Instname2
Population and Public Health
Theme2
Health systems / services
Prcname2
Public, Community & Population Health - A
Projecttitle
Development of an observational database of clinical characteristics and outcomes among HIV+ adults and children in Uganda.
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$293,606
Cihrequipment2
$0
Programname2
Operating Grant - PA: HIV/AIDS Res Initiative - Hlth Svs/Population Hlth Stream
Keyworddelim
Epidemiology; Global Health; Hiv/Aids; International Health
Abstract
Determining the best clinical care for HIV/AIDS is of utmost importance in sub-Saharan Africa. Evaluating the natural progression of HIV/AIDS and also co-infections can determine important public health outcomes for planning and intervening in the epidemic. We propose to work with the oldest and largest community-based AIDS organization in Africa, The AIDS Support Organization (TASO), to develop a database suitable for operational research and clinical research to determine patient outcomes, programme implementation, and predict future clinical outcomes. This database currently has accurate data on more than 24,000 patients receiving antiretroviral therapy and a further 80,000 patients receiving pre-antiretroviral clinical care. We now must organize this database for the purpose of large-scale research. We aim to determine the following specific research questions: 1) What CD4 T-cell threshold should be used for treatment initiation? 2) What is the expected duration of survival for patients receiving antiretroviral therapy in Uganda? This will be the largest observational study for HIV/AIDS in the developing world.
Competitiondate
200903
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Mills, Edward J
Approvedterm
3 ans 0 mois
Cihrcontribution2
Science Policy 4~ $293,606~ $0~
