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Grant: Canada Research Chairs

Institut national de la recherche scientifique

$200,000.00

Ecotoxicogenomics and Endocrine Disruption

FY 2024-25

Summary
The number and levels of contaminants in the environment have dramatically risen over the last 10 years. To address this crisis, there is an urgent need for innovative approaches to systematically characterize complex cocktails of environmental contaminants and determine their toxicity to aquatic and terrestrial organisms. This Research Chair uses state-of-the-art methodology in comparative ecotoxicogenomics and endocrinology to determine how environmental contaminants (alone and in mixtures) affect animal and ecosystem health from the molecular to population levels of organization. The goals of the research program are to 1) fundamentally rethink the way endocrine axes are currently understood to better interpret the harmful effects of endocrine disrupting chemicals; 2) determine the effects of emerging contaminants on animal health; and 3) characterize their potential toxicity on relevant indicator species, providing guidance for the development of rigorous cumulative effect risk assessments that will lead to the implementation of preventative and remedial policies and practices. This Chair is assisting Canada’s policy makers to better manage the risk of contaminants to environmental health.
Program
Canada Research Chairs
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data

As published

Application id
CRC-2022-00306
Name nom
Langlois, Valérie
Department département
Centre Eau Terre Environnement - Institut national de la recherche scientifique
Organization id
56
Institution établissement
Institut national de la recherche scientifique
Province en
Québec
Province fr
Québec
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2024
Competition year année de concours
2022
Award amount
200000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
9999
Research subject group en
Not available
Research subject group fr
Non disponible
Research subject en
Not available
Research subject fr
Non disponible
Field of research list codes
RDF1050813
Field of research list names en
Ecotoxicology
Field of research list names fr
Écotoxicologie
Socioeconomic objective list codes
RDS10299
Socioeconomic objective list names en
Environment protection, n.e.c.
Socioeconomic objective list names fr
Protection de l'environnement, n.c.a.
Application title
Ecotoxicogenomics and Endocrine Disruption
Keywords
Ecotoxicogenomics; Environmental and Chemical Toxicology; Endocrine Disruption; Comparative Physiology and Endocrinology; Molecular Biology; Environmental DNA; Molecular Tool Development
Application summary
The number and levels of contaminants in the environment have dramatically risen over the last 10 years. To address this crisis, there is an urgent need for innovative approaches to systematically characterize complex cocktails of environmental contaminants and determine their toxicity to aquatic and terrestrial organisms. This Research Chair uses state-of-the-art methodology in comparative ecotoxicogenomics and endocrinology to determine how environmental contaminants (alone and in mixtures) affect animal and ecosystem health from the molecular to population levels of organization. The goals of the research program are to 1) fundamentally rethink the way endocrine axes are currently understood to better interpret the harmful effects of endocrine disrupting chemicals; 2) determine the effects of emerging contaminants on animal health; and 3) characterize their potential toxicity on relevant indicator species, providing guidance for the development of rigorous cumulative effect risk assessments that will lead to the implementation of preventative and remedial policies and practices. This Chair is assisting Canada’s policy makers to better manage the risk of contaminants to environmental health.