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Grant: DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

University of Alberta

$120,000.00

Reframing "Pregnancy Brain": Integrative Insights into Cognitive Patterns, Mechanisms, and Interventions

FY 2025-26

Summary
Many pregnant individuals notice changes in memory, focus, and decision-making-a common experience often called "pregnancy brain." While these symptoms are widely recognized, their impact on long-term brain health is not well understood, and few strategies exist to support mental clarity during pregnancy. Physical activity(PA) is known to benefit brain function in other groups, but its effect on the brain during pregnancy has not yet been studied in detail. This project aims to understand how different PA patterns influence thinking skills during pregnancy. It includes three parts. First, we will review all existing studies on PA and cognitive function in pregnancy. Second, we will follow a group of women from before pregnancy through to the third trimester. At each stage, we will measure PA using wearable devices, assess blood flow in the brain using ultrasound, and use computer tasks to test memory, attention, and flexible thinking. We will also collect hormone and cardiovascular data to explore potential physiological pathways. In the final study, we will test whether short exercise breaks during long periods of sitting can improve thinking in late pregnancy. Participants will complete two lab visits: one with uninterrupted sitting, and one with light activity breaks. We will compare their performance on cognitive tasks before and after each session. Our results will help create more complete PA guidelines that consider not only physical health but also brain health. This may help pregnant individuals feel more mentally clear and confident during a critical life stage, and support healthy brain development for both mothers and their children.
Program
DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)
Location
Alberta, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
559928
Name
Ruan Weiqi
Region
Alberta
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Biomedical
Prcname2
DT1 (Biomedical and/or Clinical Research) CGRS Doctoral
Projecttitle
Reframing "Pregnancy Brain": Integrative Insights into Cognitive Patterns, Mechanisms, and Interventions
Programtype2
Studentship Programs
Orgnameinp2
University of Alberta
Cihramount2
$120,000
Cihrequipment2
$0
Programname2
DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)
Keyworddelim
Accelerometry; Cerebral Blood Flow; Cognitive Function; Functional Near-Infrared Spectroscopy; Hormones; Maternal Health; Neurovascular Coupling; Physical Activity; Pregnancy; Sedentary Behavior
Abstract
Many pregnant individuals notice changes in memory, focus, and decision-making-a common experience often called "pregnancy brain." While these symptoms are widely recognized, their impact on long-term brain health is not well understood, and few strategies exist to support mental clarity during pregnancy. Physical activity(PA) is known to benefit brain function in other groups, but its effect on the brain during pregnancy has not yet been studied in detail. This project aims to understand how different PA patterns influence thinking skills during pregnancy. It includes three parts. First, we will review all existing studies on PA and cognitive function in pregnancy. Second, we will follow a group of women from before pregnancy through to the third trimester. At each stage, we will measure PA using wearable devices, assess blood flow in the brain using ultrasound, and use computer tasks to test memory, attention, and flexible thinking. We will also collect hormone and cardiovascular data to explore potential physiological pathways. In the final study, we will test whether short exercise breaks during long periods of sitting can improve thinking in late pregnancy. Participants will complete two lab visits: one with uninterrupted sitting, and one with light activity breaks. We will compare their performance on cognitive tasks before and after each session. Our results will help create more complete PA guidelines that consider not only physical health but also brain health. This may help pregnant individuals feel more mentally clear and confident during a critical life stage, and support healthy brain development for both mothers and their children.
Competitiondate
202511
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Ruan, Weiqi
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $120,000~ $0~
University of Alberta - $120,000 Grant (2025-26) | Canada Spends