Grant: Project Grant

Multiple studies have shown that panic disorder (PD) and generalized anxiety disorder (GAD) are up to fifteen times more prevalent in patients with coronary artery disease than in the general population. These anxiety disorders have also been associated with a higher risk of further cardiac events such as myocardial infarction in patients with coronary artery disease. However, some contradictory results shed doubts on these conclusions. Considering the contradictory data and significant methodological issues found in the scientific literature, notably in terms of the validity of panic disorder and generalized anxiety disorder diagnoses, new studies are essential to improve our understanding of this clinical problem as well as patient care. In this context, this study aims to establish the prevalence of panic disorder and generalized anxiety disorder in 3610 patients with coronary artery disease. Another objective is to document, over a period of 2 years, the impact of these anxiety disorder on the course of coronary artery disease, quality of life, psychological distress as well as adherence to treatments and risk-reducing lifestyle changes.