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Grant: Engage Plus Grants Program

Wilfrid Laurier University

$12,500.00

Understanding phytoglycan nanoparticles' ability to modulate the innate immune response

FY 2015-16

Summary
The innate immune system is the first line of defense against invading disease-causing organisms, acting to protect animals immediately following infection. It is also an important regulator, which influences vaccine efficacy, autoimmunity, and inflammatory responses. We are pursuing novel uses for Phytospherix (PHX), a glycogen-based nanoparticle that is natural, biodegradable, non-toxic and easily modifiable. The current NSERC Engage Plus will fund research to investigate the role of PHX in controlling innate immune responses in animals, including fish and human cells. This work has long-term implications for developing novel antiviral therapies, vaccine adjuvants and anti-inflammatory drugs.
Program
Engage Plus Grants Program
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data

As published

Application id
490968-2015
Name nom
DeWitteOrr, Stephanie
Department département
Biology
Organization id
35
Institution établissement
Wilfrid Laurier University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2015
Competition year année de concours
2015
Award amount
12500
Program id
EGP2
Program name en
Engage Plus Grants Program
Program name fr
Programme de subvention d'engagement partenarial Plus
Group en
Research partnerships programs
Group fr
Programmes de partenariat
Committee code
1553
Committee name en
Ontario Internal Decision Committee
Committee name fr
Comité de décision interne pour l'Ontario
Area of application code
106
Area of application group en
Agriculture and primary food production
Area of application group fr
Agriculture et produits alimentaires primaires
Area of application en
Aquaculture
Area of application fr
Aquiculture
Research subject code
5100
Research subject group en
Cell biology
Research subject group fr
Biologie cellulaire
Research subject en
Cell biology
Research subject fr
Biologie cellulaire
Partie
1
Nb partie
1
Application title
Understanding phytoglycan nanoparticles' ability to modulate the innate immune response
Keyword
NSERC
Application summary
The innate immune system is the first line of defense against invading disease-causing organisms, acting to protect animals immediately following infection. It is also an important regulator, which influences vaccine efficacy, autoimmunity, and inflammatory responses. We are pursuing novel uses for Phytospherix (PHX), a glycogen-based nanoparticle that is natural, biodegradable, non-toxic and easily modifiable. The current NSERC Engage Plus will fund research to investigate the role of PHX in controlling innate immune responses in animals, including fish and human cells. This work has long-term implications for developing novel antiviral therapies, vaccine adjuvants and anti-inflammatory drugs.