Grant: Applied Research and Development Grants - Level 1
C.E.G.E.P. Lévis-Lauzon
$25,000.00
Efficiency of Ginnalin A in an inflammatory-induced colitis model
FY 2017-18
Summary
This project aims to assess the biological efficacy of Ginnalin A, a phenolic antioxidant compound extracted from red maples buds, in the treatment of inflammatory bowel disease using a murine model. TransBIOTech will first perform a standard pharmacokinetic analysis of Ginnalin A to establish compound bioavailability and proper dosage for the efficacy study. Using the DSS-induced colitis murine model, TransBIOTech will further establish the capability of Ginnalin A at reducing the model associated symptoms at the macroscopical, histological and biochemical levels.
Program
Applied Research and Development Grants - Level 1
Recipient
Location
Quebec, Canada
Type
Grant
Source
NSERC's Awards Data
As published
Application id
520535-2017
Name nom
Fortier, Isabelle
Department département
Siège social
Organization id
21757
Institution établissement
C.E.G.E.P. Lévis-Lauzon
Province en
Québec
Province fr
Québec
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2017
Competition year année de concours
2017
Award amount
25000
Program id
CARD1
Program name en
Applied Research and Development Grants - Level 1
Program name fr
Subventions de recherche et développement appliquée - niveau 1
Group en
Research partnerships programs
Group fr
Programmes de partenariat
Committee code
1561
Committee name en
Applied Research and Development Grants
Committee name fr
Subventions de recherche et développement appliquée
Area of application code
103
Area of application group en
Agriculture and primary food production
Area of application group fr
Agriculture et produits alimentaires primaires
Area of application en
Plant production and plant primary products
Area of application fr
Production végétale et produits végétaux primaires
Research subject code
1303
Research subject group en
Forest engineering
Research subject group fr
Génie forestier
Research subject en
Wood science and engineering
Research subject fr
Science et génie du bois
Partie
1
Nb partie
1
Application title
Efficiency of Ginnalin A in an inflammatory-induced colitis model
Keyword
NSERC
Application summary
This project aims to assess the biological efficacy of Ginnalin A, a phenolic antioxidant compound extracted from red maples buds, in the treatment of inflammatory bowel disease using a murine model. TransBIOTech will first perform a standard pharmacokinetic analysis of Ginnalin A to establish compound bioavailability and proper dosage for the efficacy study. Using the DSS-induced colitis murine model, TransBIOTech will further establish the capability of Ginnalin A at reducing the model associated symptoms at the macroscopical, histological and biochemical levels.
