Grant: Discovery Grants Program - Individual
Laurentian University of Sudbury
$20,000.00
Surface-coated metal nanoparticles with carbohydrate polymers as
FY 2007-08
Summary
Surface coated metal nanoparticles as therapeutic delivery agents are revolutionizing biomedical technologies. Currently there are several approaches being developed for cell-specific targeting of nanoparticles from systemic administration, but the fate of these particles inside the cell/body is often not well controlled. Our research focuses on developing advanced multifunctional nano-based materials that overcome transport limitations in tissues and within cells. Our goal is to prepare surface coated metal nanoparticles with well-defined carbohydrate polymers for improved solubility and stability (less aggregation in complex mixture), more resistance to surface adsorption, prolonged circulation time in bloodstream, reduced protein and cell adherence, reduced toxicity and reduced foreign body response in tissues.
Program
Discovery Grants Program - Individual
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
311962-2006
Name nom
Narain, Ravin
Department département
Chemistry and Biochemistry
Organization id
26
Institution établissement
Laurentian University of Sudbury
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2007
Competition year année de concours
2006
Award amount
20000
Program id
RGPIN
Program name en
Discovery Grants Program - Individual
Program name fr
Programme de subventions à la découverte - individuelles
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
24
Committee name en
Inorganic & Organic Chemistry
Committee name fr
Chimie inorg. et org.
Area of application code
1102
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Biomedical engineering
Area of application fr
Génie biomédical
Research subject code
2006
Research subject group en
Materials science and technology
Research subject group fr
Science et technologie des matériaux
Research subject en
Biomaterials
Research subject fr
Biomatériaux
Partie
2
Nb partie
3
Application title
Surface-coated metal nanoparticles with carbohydrate polymers as
Keyword
NA
Application summary
Surface coated metal nanoparticles as therapeutic delivery agents are revolutionizing biomedical technologies. Currently there are several approaches being developed for cell-specific targeting of nanoparticles from systemic administration, but the fate of these particles inside the cell/body is often not well controlled. Our research focuses on developing advanced multifunctional nano-based materials that overcome transport limitations in tissues and within cells. Our goal is to prepare surface coated metal nanoparticles with well-defined carbohydrate polymers for improved solubility and stability (less aggregation in complex mixture), more resistance to surface adsorption, prolonged circulation time in bloodstream, reduced protein and cell adherence, reduced toxicity and reduced foreign body response in tissues.
