Grant: Discovery Grants Program - Individual
Trinity Western University
$28,000.00
Elucidating the role of unc-53 and its molecular partners in actin mediated processes
FY 2009-10
Summary
Changes in cell shape are associated with a variety of developmental processes including cell migration, patterning of the nervous system, cell division, and transport of molecules in and out of the cell. We have been studying the role of the navigators, molecules that are required for the migration of cells and neuronal processes in both worms and humans, and have shown that they exert their influence by re-organizing actin filaments, the network of cables that make up part of the cytoskeleton and control cell shape changes. The objectives of my research program are to elucidate the role of the navigators and their molecular partners in actin cytoskeleton processes such as cell migration and the trafficking of molecules inside the cell. These studies have implications for diseases such as cancer, as well as neurodegenerative disorders, and healing after neural injury.
Program
Discovery Grants Program - Individual
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
217729-2008
Name nom
Stringham, Eve
Department département
Biology
Organization id
6
Institution établissement
Trinity Western University
Province en
British Columbia
Province fr
Colombie-Britannique
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2009
Competition year année de concours
2008
Award amount
28000
Program id
RGPIN
Program nane en
Discovery Grants Program - Individual
Program name fr
Programme de subventions à la découverte - individuelles
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
33
Committee name en
Molec. & Develop. Genetics
Committee name fr
Gén. moléculaire et dévelop.
Area of application code
1200
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Advancement of knowledge
Area of application fr
Avancement des connaissances
Research subject code
5003
Research subject group en
Genetics
Research subject group fr
Génétique
Research subject en
Developmental genetics
Research subject fr
Génétique du développement
Partie
2
Nb partie
3
Application title
Elucidating the role of unc-53 and its molecular partners in actin mediated processes
Keyword
NA
Application summary
Changes in cell shape are associated with a variety of developmental processes including cell migration, patterning of the nervous system, cell division, and transport of molecules in and out of the cell. We have been studying the role of the navigators, molecules that are required for the migration of cells and neuronal processes in both worms and humans, and have shown that they exert their influence by re-organizing actin filaments, the network of cables that make up part of the cytoskeleton and control cell shape changes. The objectives of my research program are to elucidate the role of the navigators and their molecular partners in actin cytoskeleton processes such as cell migration and the trafficking of molecules inside the cell. These studies have implications for diseases such as cancer, as well as neurodegenerative disorders, and healing after neural injury.
