Grant: Foundation Grant
Ottawa Hospital Research Institute
$3,702,580.00
Investigating Virus-Host Interactions to Design Viral Anti Cancer Therapeutics
FY 2015-16
Summary
Anti-cancer biotherapeutics built from viruses have begun to emerge as potential new ways to safely and effectively treat cancer. Our work has shown that viruses can be safely administered to cancer patients and in some cases can lead to complete tumor eradication even in advanced patients. This project is aimed at building on this work to create improved virus based therapeutics that alone, or in combination with other therapies, leads to complete responses in a larger proportion of patients. We will use large collections of viruses and explore their abilities to kill cancer cells with the goal of finding more effective therapeutics.
Department
Program
Foundation Grant
Recipient
Location
Ontario, Canada
Recipient Type
Other
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
333630
Name
Bell John C
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Foundation Grant
Projecttitle
Investigating Virus-Host Interactions to Design Viral Anti Cancer Therapeutics
Programtype2
Operating Grants
Orgnameinp2
Ottawa Hospital Research Institute
Cihramount2
$3,702,580
Cihrequipment2
$0
Programname2
Foundation Grant
Keyworddelim
Antiviral; Cancer; Crispr/Cas9; Genome Editing; Immunotherapy; Manufacturing; Next Generation Sequencing; Oncolytic Viruses; Screening; Vaccines
Abstract
Anti-cancer biotherapeutics built from viruses have begun to emerge as potential new ways to safely and effectively treat cancer. Our work has shown that viruses can be safely administered to cancer patients and in some cases can lead to complete tumor eradication even in advanced patients. This project is aimed at building on this work to create improved virus based therapeutics that alone, or in combination with other therapies, leads to complete responses in a larger proportion of patients. We will use large collections of viruses and explore their abilities to kill cancer cells with the goal of finding more effective therapeutics.
Competitiondate
201509
Approvedterm2
7 yrs 0 mth
Pinamesdelim
Bell, John C
Approvedterm
7 ans 0 mois
Cihrcontribution2
~ $3,702,580~ $0~
