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Grant: Project Grant

University of British Columbia

$180,000.00

A Precision Public Health Approach to Eliminating Tuberculosis Transmission: Using Linked Genomic and Administrative Data to Prevent Outbreaks

FY 2017-18

Summary
Canada is struggling to achieve tuberculosis (TB) elimination and new, innovative strategies for reducing TB rates are required. Our team pioneered the use of genomics - DNA sequencing - to understand how TB transmits from person to person in Canada, and we have recently completed a large genomic investigation aimed at identifying all transmitted TB in BC from 2005-2014. Now, we want to understand this transmission at a deeper level. By linking our genomic data to a variety of other data sources, we hope to be able to predict who is most likely to transmit TB onwards and which small clusters of TB cases are at risk of growing into large outbreaks. Armed with this information, public health practitioners on the frontlines of TB control will be better equipped to proactively prevent TB transmission, and help Canada achieve our goal of TB elimination.
Program
Project Grant
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
380480
Name
Gardy Jennifer L
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Population and Public Health
Theme2
Social / Cultural / Environmental / Population Health
Prcname2
Public, Community & Population Health
Projecttitle
A Precision Public Health Approach to Eliminating Tuberculosis Transmission: Using Linked Genomic and Administrative Data to Prevent Outbreaks
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$180,000
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Genomic Epidemiology; Genomics; Outbreak; Risk; Transmission; Tuberculosis
Abstract
Canada is struggling to achieve tuberculosis (TB) elimination and new, innovative strategies for reducing TB rates are required. Our team pioneered the use of genomics - DNA sequencing - to understand how TB transmits from person to person in Canada, and we have recently completed a large genomic investigation aimed at identifying all transmitted TB in BC from 2005-2014. Now, we want to understand this transmission at a deeper level. By linking our genomic data to a variety of other data sources, we hope to be able to predict who is most likely to transmit TB onwards and which small clusters of TB cases are at risk of growing into large outbreaks. Armed with this information, public health practitioners on the frontlines of TB control will be better equipped to proactively prevent TB transmission, and help Canada achieve our goal of TB elimination.
Competitiondate
201803
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Gardy, Jennifer L; Johnston, James C
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $180,000~ $0~