Grant: Operating Grant - PA: Bridge Funding -CHVI Vaccine Discovery and Social Research
University of Manitoba
$100,000.00
Defining the mechanisms of IRF1 in mediating innate resistance to mucosal HIV acquisition in HIV exposed seronegative (HESN) women.
FY 2012-13
Summary
The ultimate solution to the HIV/AIDS pandemic, still, one of the greatest health issues facing humankind, is the development of an effective vaccine or microbicide. Almost all vaccines were derived out of an understanding, no matter how primitive, of what results in protective immunity. We seek to understand the mechanisms of natural protection against HIV in women who are highly exposed to HIV yet escape infection. Determining the mechanism(s) protecting these women from HIV, may lead to new knowledge and the eventual development of an effective HIV vaccine, microbicide or novel prevention strategy.
Department
Program
Operating Grant - PA: Bridge Funding -CHVI Vaccine Discovery and Social Research
Recipient
Location
Manitoba, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
277855
Name
Ball Terry B
Region
Manitoba
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Infection and Immunity
Theme2
Biomedical
Prcname2
Virology & Viral Pathogenesis
Projecttitle
Defining the mechanisms of IRF1 in mediating innate resistance to mucosal HIV acquisition in HIV exposed seronegative (HESN) women.
Programtype2
Operating Grants
Orgnameinp2
University of Manitoba
Cihramount2
$100,000
Cihrequipment2
$0
Programname2
Operating Grant - PA: Bridge Funding -CHVI Vaccine Discovery and Social Research
Keyworddelim
Africa; Genetics; Hesn; Hiv; Innate; Irf1; Microbicide; Mucosal; Prevention; Resistance
Abstract
The ultimate solution to the HIV/AIDS pandemic, still, one of the greatest health issues facing humankind, is the development of an effective vaccine or microbicide. Almost all vaccines were derived out of an understanding, no matter how primitive, of what results in protective immunity. We seek to understand the mechanisms of natural protection against HIV in women who are highly exposed to HIV yet escape infection. Determining the mechanism(s) protecting these women from HIV, may lead to new knowledge and the eventual development of an effective HIV vaccine, microbicide or novel prevention strategy.
Competitiondate
201209
Approvedterm2
1 yr 0 mth
Pinamesdelim
Ball, Terry B
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $100,000~ $0~
