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Grant: Operating Grant

Université de Sherbrooke

$338,166.00

Understanding the contribution of ovarian cancer ascites to drug and death receptor resistance

FY 2010-11

Summary
Dr Piché is working to characterize the effects that ovarian cancer ascites, a peritoneal fluid that accumulates during ovarian cancer progression, may have on enhancing drug resistance and disease-free progression. This work will identify soluble factors in ascites that affect tumor cell sensitivity to drugs, will define the intracellular mechansims involved, will identify new biomarker for early relapse and potential new therapeutic targets.
Program
Operating Grant
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
224067
Name
Piche Alain
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Cancer Progression & Therapeutics
Projecttitle
Understanding the contribution of ovarian cancer ascites to drug and death receptor resistance
Programtype2
Operating Grants
Orgnameinp2
Université de Sherbrooke
Cihramount2
$338,166
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Death Receptor Resistance; Drug Resistance; Ovarian Cancer Ascites; Tumor Microenvironment
Abstract
Dr Piché is working to characterize the effects that ovarian cancer ascites, a peritoneal fluid that accumulates during ovarian cancer progression, may have on enhancing drug resistance and disease-free progression. This work will identify soluble factors in ascites that affect tumor cell sensitivity to drugs, will define the intracellular mechansims involved, will identify new biomarker for early relapse and potential new therapeutic targets.
Competitiondate
201103
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Piche, Alain
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $338,166~ $0~