Grant: Meetings, Planning and Dissemination Grant: Gender, Sex and Health

GENESIS PRAXY (PRemature Acute Coronary Syndrome) Study will explore sex differences and their determinants in several important aspects of premature ACS. This will be the first large prospective cohort study in Canada to comprehensively address sex differences in prognostic, health services utilization, and diagnostic aspects of premature ACS. This multi-pronged project will be comprised of two major components: (i) a cross-sectional study with prospective recruitment of young ACS patients; and, (ii) a case-only study with prospective follow-up of young ACS patients. GENESIS PRAXY will include 1,576 ACS patients, 18-50 years of age, enrolled over 3 years from 30 participating hospitals across Canada. The GENESIS-PRAXY Research Team will be meeting in October 2010 to allow all site PI's and Co-Investigators to meet for an Annual International Montreal Conference where this event will contribute greatly to the dissemination, exchange an uptake of evidence on gender, sex and health research. By inviting the PI of the VIRGO team at Yale, Dr. Harlan Krumholz and Dr. Judith Lichtman, VIRGO Study Co-Principal Investigator we wish to foster development of an international partnership, focused on the health research of ACS in young adults. VIRGO and GENESIS-PRAXY have many similarities. Both bridge disciplines from basic biology to clinical sciences to psychology and health services research. VIRGO investigators will be working closely with the American Heart Association to disseminate study findings as GENESIS-PRAXY will be working closely with CIHR and the Heart & Stroke of Canada.