Grant: Operating Grant
Ottawa Hospital Research Institute
$100,000.00
Regulation of cell motility by teh Ste20-like kinase SLK
FY 2008-09
Summary
Cell migration is an important component of cancer cell invasion and metastasis. We propose to investigate the molecular mechanisms regulating the Ste20 like kinase SLK, a regulator of cel migration. Using in vivo and in vitro approaches we will look into the upstream and downstream SLK-dependent signaling. These studies may validate SLK as a potential novel therapeutic target for the treatment of aggressive cancers.
Department
Program
Operating Grant
Recipient
Location
Ontario, Canada
Recipient Type
Other
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
183791
Name
Sabourin Luc A
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Molecular & Cellular Biology of Cancer
Projecttitle
Regulation of cell motility by teh Ste20-like kinase SLK
Programtype2
Operating Grants
Orgnameinp2
Ottawa Hospital Research Institute
Cihramount2
$100,000
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Cell Migration; Kinases; Signaling
Abstract
Cell migration is an important component of cancer cell invasion and metastasis. We propose to investigate the molecular mechanisms regulating the Ste20 like kinase SLK, a regulator of cel migration. Using in vivo and in vitro approaches we will look into the upstream and downstream SLK-dependent signaling. These studies may validate SLK as a potential novel therapeutic target for the treatment of aggressive cancers.
Competitiondate
200810
Approvedterm2
1 yr 0 mth
Pinamesdelim
Sabourin, Luc A
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $100,000~ $0~
