Grant: Catalyst Grant: Breathing as One - Boehringer Ingelheim Canada COPD Grant
Ottawa Hospital Research Institute
$15,000.00
A Pilot Feasibility Study to Inform the Development of a Novel Clinical and Biomarker-driven Definition of COPD Exacerbation among Hospitalized Adults in Canada
FY 2020-21
Summary
There is no objective gold standard definition for an exacerbation of COPE (COPDe). The consensus definition, "an accute worsening of respiratory symptoms that result in additional therapy". is highly subjective with several disadvantages. The definition lacks objective data (i.e. biomarkers) making it vulnerable to variation between patients, and there is no means to differentiate between exacerbations of common comorbid conditions including acute heart failure of pneumonia, which present with similar respiratory symptoms. To improve the diagnosis and treatments for COPDe, it is imperative to capture a definition that is objective and highly specific.
Department
Program
Catalyst Grant: Breathing as One - Boehringer Ingelheim Canada COPD Grant
Recipient
Location
Ontario, Canada
Recipient Type
Other
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
446102
Name
Mulpuru Sunita
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
Canadian Lung Association (Ottawa)
Prcname2
Special Cases
Projecttitle
A Pilot Feasibility Study to Inform the Development of a Novel Clinical and Biomarker-driven Definition of COPD Exacerbation among Hospitalized Adults in Canada
Programtype2
Operating Grants
Orgnameinp2
Ottawa Hospital Research Institute
Cihramount2
$15,000
Cihrequipment2
$0
Programname2
Catalyst Grant: Breathing as One - Boehringer Ingelheim Canada COPD Grant
Keyworddelim
Biomarkers; Copd; Exacerbations; Feasibility Study
Abstract
There is no objective gold standard definition for an exacerbation of COPE (COPDe). The consensus definition, "an accute worsening of respiratory symptoms that result in additional therapy". is highly subjective with several disadvantages. The definition lacks objective data (i.e. biomarkers) making it vulnerable to variation between patients, and there is no means to differentiate between exacerbations of common comorbid conditions including acute heart failure of pneumonia, which present with similar respiratory symptoms. To improve the diagnosis and treatments for COPDe, it is imperative to capture a definition that is objective and highly specific.
Competitiondate
202102
Approvedterm2
1 yr 0 mth
Pinamesdelim
Mulpuru, Sunita
Approvedterm
1 an 0 mois
Cihrcontribution2
Inst of Circ &Respiratory Hlth~ $15,000~ $0~
