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Grant: Project Grant

University of British Columbia

$914,176.00

Targeting lung microbiome for developing early detection and intervention strategies for lung cancer

FY 2021-22

Summary
Bacteria residing in the human lung may contribute to cancer development. This study determines whether specific changes in bacterial composition in the airways is indicative of cancer development and if the bacteria living in lung tumours are supplying essential nutrients (that cannot be produced by human cells) to support tumour growth. Knowledge gained from this project will facilitate development of innovative strategies for early detection (by detecting bacterial-related changes prior to clinical diagnosis) and early intervention of lung cancer (by targeting bacteria living in the tumour in order to starve cancer cells).
Program
Project Grant
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
462629
Name
Lam Wan L
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Cancer Research
Theme2
Biomedical
Prcname2
Cancer Progression & Therapeutics
Projecttitle
Targeting lung microbiome for developing early detection and intervention strategies for lung cancer
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$914,176
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Early Detection; Lung Cancer; Microbiome; Molecular Biology
Abstract
Bacteria residing in the human lung may contribute to cancer development. This study determines whether specific changes in bacterial composition in the airways is indicative of cancer development and if the bacteria living in lung tumours are supplying essential nutrients (that cannot be produced by human cells) to support tumour growth. Knowledge gained from this project will facilitate development of innovative strategies for early detection (by detecting bacterial-related changes prior to clinical diagnosis) and early intervention of lung cancer (by targeting bacteria living in the tumour in order to starve cancer cells).
Competitiondate
202203
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Lam, Wan L
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $914,176~ $0~