Grant: Operating Grant

Preeclampsia is a complication of pregnancy related to adverse maternal and neonatal outcomes, including fetal growth restriction and perinatal death. Several measures are used of under investigation (low-dose aspirin, low-molecular weight heparin, calcium, folic acid, among others) for the prevention of preeclampsia. Unfortunately, most high-risk women who could benefit from those preventive measures are not identified until too late in pregnancy. However, recent evidences suggest that we could identify women at risk of developping preeclampsia using a comination of serum and ultrasound biomarkers in the first-trimester of pregnancy. This screening test needs to be validated in our population. The validation of a first-trimester screening strategy will strengthen clinical research on preeclampsia and will contribute to the development of strategy combining the prediction and prevention of the disease and its related complications.