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Grant: Collaborative Health Research Projects (NSERC partnered)

Université de Montréal

$328,059.00

Clinical evaluation of surface-plasmon resonance and nanoparticle-based fluorescent detection of serum biomarkers

FY 2012-13

Summary
Our team has developed new technology that will allow the rapid detection of blood-borne disease markers, or allow monitoring drug concentrations during treatment. Our affordable, portable prototype apparatus is based on optical detection, using recent innovations to increase sensitivity. Our innovations will allow the detection using small volumes of blood, such that the method is non-invasive. The technology is readily adaptable to detection of a large number of approved biomarkers and can be applied to monitoring the blood concentrations of specific drugs. This project entails the development of detection protocols for blood-borne molecules, related to cancer therapy. The focus will be on the detection of prostate cancer, and on monitoring the course of treatment of childhood amyloid lymphoblastic leukemia. The technology developers will collaboratively adapt the detection assays to the current needs and clinical reality of clinicians from major health centers in Montreal. The assays will be rapidly integrated into clinical environments for validation. Our team is committed to the commercial development of this technology.
Program
Collaborative Health Research Projects (NSERC partnered)
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
270225
Name
Pelletier Joelle N
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Partnername
Natural Sciences and Engineering Research Council of Canada (NSERC)
Instname2
Genetics
Theme2
Biomedical
Prcname2
Collaborative Health Research Projects - NSERC Partnered
Projecttitle
Clinical evaluation of surface-plasmon resonance and nanoparticle-based fluorescent detection of serum biomarkers
Programtype2
Operating Grants
Orgnameinp2
Université de Montréal
Cihramount2
$328,059
Cihrequipment2
$0
Programname2
Collaborative Health Research Projects (NSERC partnered)
Keyworddelim
Cancer Biomarker; Cancer Treatment; Fluorescence; Nanoparticle; Pharmacokinetics; Portable Device; Surface Plasmon Resonance; Ultra-Low Fouling Surfaces
Abstract
Our team has developed new technology that will allow the rapid detection of blood-borne disease markers, or allow monitoring drug concentrations during treatment. Our affordable, portable prototype apparatus is based on optical detection, using recent innovations to increase sensitivity. Our innovations will allow the detection using small volumes of blood, such that the method is non-invasive. The technology is readily adaptable to detection of a large number of approved biomarkers and can be applied to monitoring the blood concentrations of specific drugs. This project entails the development of detection protocols for blood-borne molecules, related to cancer therapy. The focus will be on the detection of prostate cancer, and on monitoring the course of treatment of childhood amyloid lymphoblastic leukemia. The technology developers will collaboratively adapt the detection assays to the current needs and clinical reality of clinicians from major health centers in Montreal. The assays will be rapidly integrated into clinical environments for validation. Our team is committed to the commercial development of this technology.
Competitiondate
201210
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Pelletier, Joelle N; Masson, Jean-Francois
Approvedterm
3 ans 0 mois
Cihrcontribution2
Institute of Genetics~ $164,028~ $0~Knowledge Translation Branch~ $164,031~ $0~