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Grant: Operating Grant

Queen's University (Kingston, Ontario)

$877,662.00

The Subfornical Organ - A critical central nervous system sensor and integrator of metabolic, cardiovascular and immune signals in the circulation.

FY 2013-14

Summary
Studies described in this proposal will describe the role of a newly discovered brain area in sensing signals in the blood stream and then controlling blood pressure, food intake, body weight and metabolism. We will specifically examine whether changes in this structure associated with obesity may also contribute to the associated co-morbidities of hypertension and diabetes collectively known as the metabolic syndrome.
Program
Operating Grant
Location
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
305386
Name
Ferguson Alastair V
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Biomedical
Prcname2
Systems & Circuits Neurosciences - A
Projecttitle
The Subfornical Organ - A critical central nervous system sensor and integrator of metabolic, cardiovascular and immune signals in the circulation.
Programtype2
Operating Grants
Orgnameinp2
Queen's University (Kingston, Ontario)
Cihramount2
$877,662
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Camp; Central Autonomic Control; Cholecystokinin; Circumventricular Organs; Gene Expression; Hypertension; Insulin; Obesity; Patch Clamp Electrophysiology
Abstract
Studies described in this proposal will describe the role of a newly discovered brain area in sensing signals in the blood stream and then controlling blood pressure, food intake, body weight and metabolism. We will specifically examine whether changes in this structure associated with obesity may also contribute to the associated co-morbidities of hypertension and diabetes collectively known as the metabolic syndrome.
Competitiondate
201403
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Ferguson, Alastair V
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $877,662~ $0~