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Grant: Engage Grants Program

Brock University

$23,792.00

Synthesis of Mosquito Oviposition Pheromone Stereoisomers and Sol-Gel Supports for Controlled Release and use in Oviposition Activity Assays

FY 2012-13

Summary
The product under development is a mosquito trap which offers improved control and monitoring of the West Nile Virus (WNV) in mosquito populations. The project is a collaborative effort with Entomogen Inc. who have been involved with WNV monitoring since it appeared in Canada in 2001. Since 1999, almost 20 000 human cases of WNV were reported in the USA alone. The disease affects all mammals and its effects are strongest in the developing world where treatment options are limited. This product uses a selective pheromone based attractant, in contrast to the current non-selective method, relying primarily on carbon dioxide based traps which are attractive for all mosquitos actively looking to feed. Selectivity is important because the WNV is transmitted only by species of mosquito within the Culex genus. Testing of Culex infected mosquitos is the most accurate indicator of WNV activity in a specific area. Selectively targeting this demographic of mosquitos for surveillance would greatly decrease the costs of WNV monitoring efforts by significantly reducing the number of test subjects. Additionally, the control of WNV through pesticide based measures is disruptive to delicate ecosystems and produces an ever growing number of pesticide-resistant mosquitos. Use of an attractant trap in conjunction with insecticides would help alleviate the environmental impact as well as slow the accumulation of resistant mosquitos. The pheromone attractant employed in the trap is selective for onlyWNV carrying mosquitos and could be adapted for either monitoring or control applications.
Program
Engage Grants Program
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data

As published

Application id
444939-2012
Name nom
Dudding, Travis
Department département
Chemistry
Organization id
22
Institution établissement
Brock University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2012
Competition year année de concours
2012
Award amount
23792
Program id
EGP
Program name en
Engage Grants Program
Program name fr
Programme de subventions d'engagement partenariat
Group en
Research partnerships programs
Group fr
Programmes de partenariat
Committee code
1553
Committee name en
Ontario Internal Decision Committee
Committee name fr
Comité de décision interne pour l'Ontario
Area of application code
1201
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Life sciences (including biotechnology)
Area of application fr
Sciences de la vie (y compris biotechnologie)
Research subject code
3701
Research subject group en
Organic chemistry
Research subject group fr
Chimie organique
Research subject en
Natural products
Research subject fr
Produits naturels
Partie
1
Nb partie
1
Application title
Synthesis of Mosquito Oviposition Pheromone Stereoisomers and Sol-Gel Supports for Controlled Release and use in Oviposition Activity Assays
Keyword
NSERC
Application summary
The product under development is a mosquito trap which offers improved control and monitoring of the West Nile Virus (WNV) in mosquito populations. The project is a collaborative effort with Entomogen Inc. who have been involved with WNV monitoring since it appeared in Canada in 2001. Since 1999, almost 20 000 human cases of WNV were reported in the USA alone. The disease affects all mammals and its effects are strongest in the developing world where treatment options are limited. This product uses a selective pheromone based attractant, in contrast to the current non-selective method, relying primarily on carbon dioxide based traps which are attractive for all mosquitos actively looking to feed. Selectivity is important because the WNV is transmitted only by species of mosquito within the Culex genus. Testing of Culex infected mosquitos is the most accurate indicator of WNV activity in a specific area. Selectively targeting this demographic of mosquitos for surveillance would greatly decrease the costs of WNV monitoring efforts by significantly reducing the number of test subjects. Additionally, the control of WNV through pesticide based measures is disruptive to delicate ecosystems and produces an ever growing number of pesticide-resistant mosquitos. Use of an attractant trap in conjunction with insecticides would help alleviate the environmental impact as well as slow the accumulation of resistant mosquitos. The pheromone attractant employed in the trap is selective for onlyWNV carrying mosquitos and could be adapted for either monitoring or control applications.