Grant: Travel Awards - Institute Community Support
McMaster University
$1,000.00
Vasopressin versus catecholaminergic vasopressors in the treatment of vasodilatory shock: A systematic review and meta-analysis of the impact on atrial fibrillation, myocardial injury and mortality
FY 2017-18
Summary
Critically ill patients frequently require medications to help support their blood pressure. Norepinephrine, a hormone related to adrenaline, is commonly used, but has important side effects. These side effects can include heart attack, heart rhythm disturbances, kidney failure and even death. Vasopressin is a natural hormone released by blood vessels and can be used in place of norepinephrine.
Our objective was to review the existing literature for clinical trials that tested vasopressin against norepinehprine in critically ill patients.
Overall, we found that treating patients with vasopressin is likely to result in reductions in heart rhythm disturbances and may result in reduced death. Reduced blood flow to limbs and digits is an important side effect.
Department
Program
Travel Awards - Institute Community Support
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
368057
Name
McIntyre William F
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Clinical
Prcname2
Institute of Circulatory and Respiratory Health
Projecttitle
Vasopressin versus catecholaminergic vasopressors in the treatment of vasodilatory shock: A systematic review and meta-analysis of the impact on atrial fibrillation, myocardial injury and mortality
Programtype2
Undefined
Orgnameinp2
McMaster University
Cihramount2
$1,000
Cihrequipment2
$0
Programname2
Travel Awards - Institute Community Support
Keyworddelim
Atrial Fibrillation; Death; Limb Ischemia; Myocardial Infarction; Shock
Abstract
Critically ill patients frequently require medications to help support their blood pressure. Norepinephrine, a hormone related to adrenaline, is commonly used, but has important side effects. These side effects can include heart attack, heart rhythm disturbances, kidney failure and even death. Vasopressin is a natural hormone released by blood vessels and can be used in place of norepinephrine.
Our objective was to review the existing literature for clinical trials that tested vasopressin against norepinehprine in critically ill patients.
Overall, we found that treating patients with vasopressin is likely to result in reductions in heart rhythm disturbances and may result in reduced death. Reduced blood flow to limbs and digits is an important side effect.
Competitiondate
201707
Approvedterm2
1 yr 0 mth
Pinamesdelim
McIntyre, William F
Approvedterm
1 an 0 mois
Cihrcontribution2
Inst of Circ &Respiratory Hlth~ $1,000~ $0~
