Contribution: Industrial Research Assistance Program – Youth Employment Program
MACH32 INC.
$30,000.00
Formulation of Drug Solution and Prototype Optimization for Intramuscular Injection
FY 2024-25 · 2024-06-01
Summary
MACH32 is developing a drug-device combination medical product for early intervention and treatment of severe hemorrhage. This device administers a large-volume dose of the antifibrinolytic drug tranexamic acid (TXA). It simplifies the delivery of TXA, a clinically proven generic drug that reduces the risk of death due to bleeding by ~ 30%. TXA is underused because it is difficult to deliver and requires intravenous access; less than 5% of eligible patients receive TXA in a timely manner. This project focuses on the development of a highly concentrated TXA formulation optimized for simple intramuscular delivery in autoinjector format.
Department
Program
Industrial Research Assistance Program – Youth Employment Program
Recipient
Location
Edmonton|Edmonton, Alberta, Canada
Recipient Type
For-profit organization
Business Number
701428310
Type
Contribution
Source
Proactive Disclosure - Grants and Contributions
Amendments
Each version of the agreement as published, oldest first, with its total as of that version. The amount above is the latest.
| Amendment | Date | Fiscal Year | Total |
|---|---|---|---|
| 0 | 2024-06-01 | 2024-25 | $30,000.00 |
| 1 | 2024-06-01 | 2024-25 | $30,000.00 |
As published
Additional Information
This agreement has been amended 1 time(s). The end date of this agreements has been modified by 59 days.
Additional Information (French)
Cet accord a été modifié 1 fois La date de fin du présent accord a été changé de 59 jours.
Agreement End Date
2025-02-28
Agreement Number
1018592
Agreement Start Date
2024-06-01
Agreement Title
Formulation of Drug Solution and Prototype Optimization for Intramuscular Injection
Agreement Title (French)
Formulation d’une solution médicamenteuse et optimisation d’un prototype pour une injection intramusculaire
Agreement Type
Contribution
Agreement Value
$30,000.00
Amendment Date
2024-12-16
Amendment Number
1
Coverage
IRAP Youth Employment Program projects stimulate wealth creation for Canada through technological innovation. | Les projets du Programme Emploi-jeunesse du PARI stimulent la création de richesse au Canada grâce à l’innovation technologique.
Description
MACH32 is developing a drug-device combination medical product for early intervention and treatment of severe hemorrhage. This device administers a large-volume dose of the antifibrinolytic drug tranexamic acid (TXA). It simplifies the delivery of TXA, a clinically proven generic drug that reduces the risk of death due to bleeding by ~ 30%. TXA is underused because it is difficult to deliver and requires intravenous access; less than 5% of eligible patients receive TXA in a timely manner. This project focuses on the development of a highly concentrated TXA formulation optimized for simple intramuscular delivery in autoinjector format.
Description (French)
MACH32 développe un produit médical combinant un médicament et un dispositif pour l’intervention précoce et le traitement des hémorragies graves. Ce dispositif administre une dose à grand volume d’acide tranexamique (TXA), un médicament antifibrinolytique. Il simplifie l’administration de TXA, un médicament générique cliniquement prouvé qui réduit d’environ 30 % le risque de décès dû à une hémorragie. Le TXA est sous-utilisé parce qu’il est difficile à administrer et qu’il nécessite un accès intraveineux ; moins de 5 % des patients éligibles reçoivent le TXA en temps voulu. Ce projet se concentre sur le développement d’une formulation de TXA hautement concentrée, optimisée pour une administration intramusculaire simple sous forme d’auto-injecteur.
Expected Results
The purpose of IRAP’s Youth Employment Program is to assist in increasing the supply of highly qualified people, promoting the benefits of advanced studies, demonstrating federal leadership by investing in the skills required to meet the needs of the knowledge economy and facilitating the transition of highly skilled young people to a rapidly changing labour market.
Expected Results (French)
Le Programme Emploi-jeunesse du PARI contribue à accroître le bassin de personnes hautement qualifiées, fait la promotion des études supérieures, démontre le leadership fédéral grâce aux investissements effectués dans l’acquisition des compétences requises pour répondre aux besoins de l’économie du savoir et facilite la transition des jeunes hautement qualifiés vers un marché du travail en évolution rapide.
Federal Riding
Edmonton--Wetaskiwin
Federal Riding (French)
Edmonton--Wetaskiwin
Federal Riding Number
48021
NAICS Code
334512
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Industrial Research Assistance Program – Youth Employment Program
Program Name (French)
Programme d’aide à la recherche industrielle – Programme emploi jeunesse
Program Purpose
The purpose of IRAP’s Youth Employment Program is to assist in increasing the supply of highly qualified people, promoting the benefits of advanced studies, demonstrating federal leadership by investing in the skills required to meet the needs of the knowledge economy and facilitating the transition of highly skilled young people to a rapidly changing labour market.
Program Purpose (French)
Le Programme Emploi-jeunesse du PARI contribue à accroître le bassin de personnes hautement qualifiées, fait la promotion des études supérieures, démontre le leadership fédéral grâce aux investissements effectués dans l’acquisition des compétences requises pour répondre aux besoins de l’économie du savoir et facilite la transition des jeunes hautement qualifiés vers un marché du travail en évolution rapide.
Recipient Business Number
701428310
Recipient City
Edmonton|Edmonton
Recipient Country
CA
Recipient Legal Name
MACH32 INC.
Recipient Postal Code
T6X 0J6
Recipient Province or Territory
AB
Recipient Type
F
Reference Number
172-2024-2025-Q1-1018592
