Grant: Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
University of Waterloo |University of Waterloo
$297,656.00
Venous Ultrasound Low-flow Complexity ANalysis
FY 2025-26 · 2025-07-15
Summary
The recent observation of a blood clot forming in the neck vein of an astronaut on the International Space Station could have been related to low or stagnant blood flow in the vein as astronauts no longer have a head-to-heart gravitational gradient during spaceflight. The current study will use novel high-frame rate ultrasound investigations of blood flow in the neck vein during parabolic flights that replicate the microgravity conditions of spaceflight. From the ultrasound signals, the research team will use vector flow imaging to assess across the full width of the vessel the potential for areas of stagnant flow that could elevate the risk for blood clot formation. These results could lead to an inflight diagnostic screening test and a tool for evaluation of potential countermeasures to prevent this serious health risk for astronauts.
Department
Program
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Location
Waterloo |Waterloo , Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
Proactive Disclosure - Grants and Contributions
As published
Agreement End Date
2027-07-15
Agreement Number
25HLSHANA3
Agreement Start Date
2025-07-15
Agreement Title
Venous Ultrasound Low-flow Complexity ANalysis
Agreement Title (French)
Projet d'analyse de la complexité à faible débit par ultrasons veineux
Agreement Type
Grant
Agreement Value
$297,656.00
Amendment Number
0
Description
The recent observation of a blood clot forming in the neck vein of an astronaut on the International Space Station could have been related to low or stagnant blood flow in the vein as astronauts no longer have a head-to-heart gravitational gradient during spaceflight. The current study will use novel high-frame rate ultrasound investigations of blood flow in the neck vein during parabolic flights that replicate the microgravity conditions of spaceflight. From the ultrasound signals, the research team will use vector flow imaging to assess across the full width of the vessel the potential for areas of stagnant flow that could elevate the risk for blood clot formation. These results could lead to an inflight diagnostic screening test and a tool for evaluation of potential countermeasures to prevent this serious health risk for astronauts.
Description (French)
L'observation récente d'un caillot sanguin se formant dans la veine du cou d'un astronaute à bord de la Station spatiale internationale pourrait être liée à un flux sanguin faible ou stagnant dans la veine, les astronautes n'étant plus soumis au gradient gravitationnel tête-cœur pendant les vols spatiaux. L'étude actuelle utilisera de nouvelles techniques d'analyse par ultrasons à haute fréquence d'images du flux sanguin dans la veine du cou lors de vols paraboliques, reproduisant les conditions de microgravité des vols spatiaux. À partir des signaux ultrasonores, l'équipe de recherche utilisera l'imagerie vectorielle du flux pour évaluer, sur toute la largeur du vaisseau, les zones potentielles de flux stagnant susceptibles d'accroître le risque de formation de caillots sanguins. Ces résultats pourraient conduire à un test de dépistage diagnostique en vol et à un outil d'évaluation des contre-mesures potentielles pour prévenir ce risque grave pour la santé des astronautes.
Expected Results
The Research component of the program provides financial support to organizations to conduct space related research and development in priority areas. It will support targeted knowledge development and innovation to sustain and enhance the Canadian capacity to use space to address national needs and priorities in the future.
Expected Results (French)
Le volet Recherche du programme offre aux organisations une aide financière qui leur permettra de mener leurs activités de recherche et développement spatiales dans des secteurs prioritaires. Ce volet appuiera le développement des connaissances et l’innovation dans les domaines ciblés de manière à soutenir et à accroître la capacité du Canada d’utiliser l’espace pour répondre aux besoins et aux priorités du pays dans le futur.
Organization Code
csa-asc
Organization
Canadian Space Agency | Agence spatiale canadienne
Program Name
Class Grant and Contribution Program to Support Research, Awareness and Learning in Space Science and Technology
Program Name (French)
Programme global de subventions et contributions à l'appui de la recherche, de la sensibilisation et de l'éducation en sciences et technologies spatiales
Program Purpose
This program supports knowledge development and innovation in the CSA's priority areas while increasing the awareness and participation of Canadians in space-related disciplines and activities.
The Research Component aims to support the development of science and technology; foster the continual development of a critical mass of researchers and highly qualified people in Canada; and support information gathering and space-related studies and research pertaining to Canadian Space Agency priorities.
Program Purpose (French)
Ce programme appuie le développement des connaissances et l'innovation dans des domaines prioritaires de l'ASC et accroît la sensibilisation et la participation des Canadiens aux disciplines et aux activités liées à l'espace.
Le volet Recherche vise à soutenir le développement des sciences et des technologies, à favoriser le développement continu d'une masse critique de chercheurs et de personnes hautement qualifiées au Canada, et à appuyer la collecte d'information, la recherche et les études relatives à l'espace en tenant compte des priorités de l'ASC.
Recipient City
Waterloo |Waterloo
Recipient Country
CA
Recipient Legal Name
University of Waterloo |University of Waterloo
Recipient Postal Code
N2L3G1
Recipient Province or Territory
ON
Recipient Type
S
Reference Number
003-2025-2026-Q2-00092