Grant: Project Grant
University of British Columbia
$436,050.00
The effect of exogenous beta-hydroxybutyrate supplementation on glucose control in type 2 diabetes
FY 2019-20
Summary
Over 3 million Canadians have type 2 diabetes, a condition where blood sugar levels are too high. High blood sugar damages blood vessels and other organs contributing to disability and early death. Our objective is to test whether a newly invented nutritional drink that contains molecules called "ketones" can lower blood sugar and improve blood vessel function in
people with type 2 diabetes. Ketones are naturally made by our bodies as a source of energy during times of starvation. In preliminary research we have recently discovered that ketones might also have the ability to lower blood sugar and reduce the toxic effects of high blood sugar. After consuming this new ketone drink blood ketone levels rise quickly (within 30 minutes), which will allow us to be the first to test whether the ketone drink can lower blood
sugar and improve the health of people with type 2 diabetes.
Department
Program
Project Grant
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
408895
Name
Little Jonathan P
Region
British Columbia
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Clinical
Prcname2
Nutrition, Food & Health
Projecttitle
The effect of exogenous beta-hydroxybutyrate supplementation on glucose control in type 2 diabetes
Programtype2
Operating Grants
Orgnameinp2
University of British Columbia
Cihramount2
$436,050
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Dietary Supplements; Endothelial Function; Glucose Control; Ketones; Metabolism; Nutrition; Postprandial Hyperglycemia; Type 2 Diabetes
Abstract
Over 3 million Canadians have type 2 diabetes, a condition where blood sugar levels are too high. High blood sugar damages blood vessels and other organs contributing to disability and early death. Our objective is to test whether a newly invented nutritional drink that contains molecules called "ketones" can lower blood sugar and improve blood vessel function in
people with type 2 diabetes. Ketones are naturally made by our bodies as a source of energy during times of starvation. In preliminary research we have recently discovered that ketones might also have the ability to lower blood sugar and reduce the toxic effects of high blood sugar. After consuming this new ketone drink blood ketone levels rise quickly (within 30 minutes), which will allow us to be the first to test whether the ketone drink can lower blood
sugar and improve the health of people with type 2 diabetes.
Competitiondate
201909
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Little, Jonathan P
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $436,050~ $0~
