Grant: CIHR-ICRH Travel Awards - General pool
Concordia University (Montreal, Quebec)
$1,500.00
Systematic analysis of mitochondrial carrier functional redundancy using complex genetic interaction analysis
FY 2023-24
Summary
I am interesting in understanding how genes that are responsible for the transport of metabolites across the mitochondrial membrane interact with each other. When these genes are mutated alone or in combination with each other, it can negatively affect cells. I want to uncover which genes when mutated or deleted in combination lead to a reduction in cell viability. I will study this in a model organism, the budding yeast, and then validate the results in human cells. I am particularly interested in this family of genes because when mutated they lead to diseases in humans. This study will help understand how changes in the genetic code leads to diseases in humans.
Department
Program
CIHR-ICRH Travel Awards - General pool
Location
Quebec, Canada
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
495442
Name
Greco Brittany
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Prcname2
Special Cases
Projecttitle
Systematic analysis of mitochondrial carrier functional redundancy using complex genetic interaction analysis
Programtype2
Undefined
Orgnameinp2
Concordia University (Montreal, Quebec)
Cihramount2
$1,500
Cihrequipment2
$0
Programname2
CIHR-ICRH Travel Awards - General pool
Keyworddelim
Mitochondrial Membrane
Abstract
I am interesting in understanding how genes that are responsible for the transport of metabolites across the mitochondrial membrane interact with each other. When these genes are mutated alone or in combination with each other, it can negatively affect cells. I want to uncover which genes when mutated or deleted in combination lead to a reduction in cell viability. I will study this in a model organism, the budding yeast, and then validate the results in human cells. I am particularly interested in this family of genes because when mutated they lead to diseases in humans. This study will help understand how changes in the genetic code leads to diseases in humans.
Competitiondate
202309
Approvedterm2
1 yr 0 mth
Pinamesdelim
Greco, Brittany
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $1,500~ $0~
