Grant: Training Grant
University of Ottawa
$1,790,000.00
CIHR Training Grant in Neurodegenerative Lipidomics: A Targeted Systems Biology Approach to Integrative Research Training
FY 2008-09
Summary
Alzheimer¿s Disease (AD) followed by Parkinson¿s Disease
(PD)are Canada¿s most common and devastating
neurodegenerative disorders. Insidious cognitive and physical
decline renders victims dependent upon custodial care at an
annual cost of $9 billion. The lack of therapeutic options has
been dubbed the ¿biggest unmet medical need in neurology¿
Arguably, the next major advance in rational therapeutic design
will come in tying a cell¿s metabolome into genomic and
proteomic maps of disease. Here, we propose an unique trans-
institutional training program in ¿lipidomics¿ designed for basic
and clinical scientists that focuses on characterizing global and
cellular changes in lipid metabolism that render neurons
vulnerable to AD and PD based at the University of Ottawa
(Ottawa Institute of Systems Biology)
and University of Toronto (Center for Research in
Neurodegenerative Disease).
Department
Program
Training Grant
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
177400
Name
Bennett Steffany A
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Biomedical
Prcname2
CIHR Training Program Grants "C"
Projecttitle
CIHR Training Grant in Neurodegenerative Lipidomics: A Targeted Systems Biology Approach to Integrative Research Training
Programtype2
Operating Grants
Orgnameinp2
University of Ottawa
Cihramount2
$1,790,000
Cihrequipment2
$0
Programname2
Training Grant
Keyworddelim
Alzheimer And Parkinson'S Disease; Cell Biology; Lipidomics; Mass Spectrometry; Neurodegenerative Disease; Systems Biology
Abstract
Alzheimer¿s Disease (AD) followed by Parkinson¿s Disease
(PD)are Canada¿s most common and devastating
neurodegenerative disorders. Insidious cognitive and physical
decline renders victims dependent upon custodial care at an
annual cost of $9 billion. The lack of therapeutic options has
been dubbed the ¿biggest unmet medical need in neurology¿
Arguably, the next major advance in rational therapeutic design
will come in tying a cell¿s metabolome into genomic and
proteomic maps of disease. Here, we propose an unique trans-
institutional training program in ¿lipidomics¿ designed for basic
and clinical scientists that focuses on characterizing global and
cellular changes in lipid metabolism that render neurons
vulnerable to AD and PD based at the University of Ottawa
(Ottawa Institute of Systems Biology)
and University of Toronto (Center for Research in
Neurodegenerative Disease).
Competitiondate
200811
Approvedterm2
6 yrs 0 mth
Pinamesdelim
Bennett, Steffany A; Figeys, Daniel
Approvedterm
6 ans 0 mois
Cihrcontribution2
Institute of Aging~ $1,790,000~ $0~
