Grant: Discovery Grants Program - Individual
University of Western Ontario
$41,000.00
Development of an Optical System to Study the Dynamic Regulation of Blood Flow and Oxygenation in the Cerebral Microvasculature.
FY 2015-16
Summary
Due to the brain's high energy demands, its blood flow is highly regulated in order to maintain a continuous supply of oxygen and nutrients. Because of the tight coupling between brain blood flow and energy metabolism, cerebrovascular dysfunction is believed to not only play a critical role in vascular diseases such as stroke, but in neurodegenerative diseases as well. This proposal will focus on the development of a non-invasive, safe optical system capable of assessing the dynamic control of brain blood flow and oxygenation. Initial experiments are aimed at confirming the accuracy of the developed technology and demonstrating its capability using healthy volunteers. Ultimately this technology could be used to better understand how diseases, such as Alzheimer's, alter the critical the link between brain blood flow and proper brain function.
Program
Discovery Grants Program - Individual
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
312450-2012
Name nom
StLawrence, Keith
Department département
Medical Biophysics
Organization id
36
Institution établissement
University of Western Ontario
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2015
Competition year année de concours
2012
Award amount
41000
Program id
RGPIN
Program name en
Discovery Grants Program - Individual
Program name fr
Programme de subventions à la découverte - individuelles
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1505
Committee name en
Physics
Committee name fr
Physique
Area of application code
1102
Area of application group en
Health, education and social services
Area of application group fr
Santé publique, éducation et services sociaux
Area of application en
Biomedical engineering
Area of application fr
Génie biomédical
Research subject code
1900
Research subject group en
Biomedical engineering
Research subject group fr
Génie biomédical
Research subject en
Biomedical engineering
Research subject fr
Génie biomédical
Partie
4
Nb partie
5
Application title
Development of an Optical System to Study the Dynamic Regulation of Blood Flow and Oxygenation in the Cerebral Microvasculature.
Keyword
NSERC
Application summary
Due to the brain's high energy demands, its blood flow is highly regulated in order to maintain a continuous supply of oxygen and nutrients. Because of the tight coupling between brain blood flow and energy metabolism, cerebrovascular dysfunction is believed to not only play a critical role in vascular diseases such as stroke, but in neurodegenerative diseases as well. This proposal will focus on the development of a non-invasive, safe optical system capable of assessing the dynamic control of brain blood flow and oxygenation. Initial experiments are aimed at confirming the accuracy of the developed technology and demonstrating its capability using healthy volunteers. Ultimately this technology could be used to better understand how diseases, such as Alzheimer's, alter the critical the link between brain blood flow and proper brain function.
