Grant: Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Kyoto University
$750,000.00
Automation of precision gene editing platform to accelerate engineering of human induced pluripotent stem cells
FY 2021-22 · 2021-04-01
Summary
Exploiting genome editing technology to engineer enhanced and novel therapeutic attributes into clinically relevant cell types represents a disruptive modality to circumvent current challenges in cell- and gene-based therapies. The goal of this Project is to establish genome engineering tools amenable to automated and high throughput platforms that facilitate the engineering of therapeutic attributes into human induced pluripotent stem cells (iPSCs). Once established, these tools will be foundational to accelerating the innovation and discovery cycles of engineered cell-based therapies with increased safety, affordability and accessibility in the space of regenerative medicine and immunotherapy.
Department
Program
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Recipient
Location
Kyoto-shi, JP
Recipient Type
Not-for-profit organization or charity
Type
Grant
Source
Proactive Disclosure - Grants and Contributions
Amendments
Each version of the agreement as published, oldest first, with its total as of that version. The amount above is the latest.
| Amendment | Date | Fiscal Year | Total |
|---|---|---|---|
| 0 | 2021-04-01 | 2021-22 | $750,000.00 |
| 1 | 2021-04-01 | 2021-22 | $750,000.00 |
As published
Additional Information
This agreement has been amended 1 time(s). The end date of this agreement has been modified by 365 days.
Additional Information (French)
Cet accord a été modifié 1 fois. La date de fin du présent accord a été changé de 365 jours.
Agreement End Date
2025-03-31
Agreement Number
991892
Agreement Start Date
2021-04-01
Agreement Title
Automation of precision gene editing platform to accelerate engineering of human induced pluripotent stem cells
Agreement Title (French)
Automatisation de la plateforme d’édition génomique de précision en vue d’un modelage plus rapide des cellules souches pluripotentes induites humaines
Agreement Type
Grant
Agreement Value
$750,000.00
Amendment Date
2024-03-20
Amendment Number
1
Description
Exploiting genome editing technology to engineer enhanced and novel therapeutic attributes into clinically relevant cell types represents a disruptive modality to circumvent current challenges in cell- and gene-based therapies. The goal of this Project is to establish genome engineering tools amenable to automated and high throughput platforms that facilitate the engineering of therapeutic attributes into human induced pluripotent stem cells (iPSCs). Once established, these tools will be foundational to accelerating the innovation and discovery cycles of engineered cell-based therapies with increased safety, affordability and accessibility in the space of regenerative medicine and immunotherapy.
Description (French)
Automatisation de la plateforme d’édition génomique de précision en vue d’un modelage plus rapide des cellules souches pluripotentes induites humaines
Expected Results
In the short term, anticipated outcomes will be strengthened collaborations across industry, academia, and government to support research excellence. In the medium term, anticipated outcomes will be the development of new and potentially disruptive technologies with collaborators. In the long term, find collaborative solutions to public policy challenges and create stronger innovation systems.
Expected Results (French)
À court terme, les résultats prévus seront des collaborations renforcées entre l'industrie, le milieu universitaire et le gouvernement pour soutenir l'excellence en recherche. À moyen terme, les résultats attendus seront le développement de nouvelles technologies potentiellement perturbatrices avec des collaborateurs. À long terme, trouver des solutions collaboratives aux défis des politiques publiques et créer des systèmes d'innovation plus solides.
NAICS Code
541710 - R&D in the physical, engineering and life sciences
Organization Code
nrc-cnrc
Organization
National Research Council Canada | Conseil national de recherches Canada
Program Name
Collaborative Science, Technology and Innovation Program - Collaborative R&D Initiatives
Program Name (French)
Programme de collaboration en science, en technologie et en innovation - Initiatives de collaboration en R-D
Program Purpose
Collaborate on multiparty research and development programs to catalyze transformative, high-risk, high-reward research with the potential for game-changing scientific discoveries and technological breakthroughs in priority areas.
Program Purpose (French)
Collaborer à des programmes multipartites de recherche-développement dans le but de profiter de la synergie entre la recherche transformatrice à haut risque et à haut rendement et le potentiel de découvertes scientifiques et de percées technologiques révolutionnaires dans des secteurs d’intervention prioritaires.
Recipient Business Number
000000000
Recipient City
Kyoto-shi
Recipient Country
JP
Recipient Legal Name
Kyoto University
Recipient Type
N
Reference Number
172-2021-2022-Q1-971037
