Grant: Canada Research Chairs
The University of British Columbia
$100,000.00
Developmental Neurobiology
FY 2023-24
Summary
My research program aims at understanding how nerve cells (neurons) communicate with their neighboring cells to form a functional neural network. Neurons communicate with their target cells via specialized interface called synapses. Miscommunication between neurons cause various neurological conditions which are detrimental to those affected and their family. Toward this I use neurons of the genetic model organism, Caenorhabditis elegans, to elucidate the genetic and molecular mechanisms that underlie where and how neurons form synapses. Our findings will help other researchers to test if similar mechanisms is present in animal models with more complex nervous system such as mouse.
Program
Canada Research Chairs
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
CRC-2019-00291
Name nom
Mizumoto, Kota
Department département
Head Office
Organization id
2
Institution établissement
The University of British Columbia
Province en
British Columbia
Province fr
Colombie-Britannique
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2023
Competition year année de concours
2019
Award amount
100000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
10000
Research subject group en
The field of research available
Research subject group fr
The field of research available
Research subject en
Le domaine de recherche disponible
Research subject fr
Le domaine de recherche disponible
Field of research list codes
RDF10602;RDF301
Field of research list names en
Cell biology;Basic medicine and life sciences
Field of research list names fr
Biologie cellulaire;Médecine fondamentale et sciences de la vie
Application title
Developmental Neurobiology
Keyword
neuron
synapse
genetics
model organism
C. elegans
developmental biology
neuroscience
gap junction
plexin
TNIK
semaphorin
Application summary
My research program aims at understanding how nerve cells (neurons) communicate with their neighboring cells to form a functional neural network. Neurons communicate with their target cells via specialized interface called synapses. Miscommunication between neurons cause various neurological conditions which are detrimental to those affected and their family. Toward this I use neurons of the genetic model organism, Caenorhabditis elegans, to elucidate the genetic and molecular mechanisms that underlie where and how neurons form synapses. Our findings will help other researchers to test if similar mechanisms is present in animal models with more complex nervous system such as mouse.
