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Grant: Operating Grant

University of Toronto

$444,989.00

The effect of a low glycemic index (GI) diet on maternal glycemic control and maternal and neonatal markers of postpartum diabetes risk in women with gestational hyperglycemia.

FY 2010-11

Summary
Women who develop gestational diabetes (high blood sugar during pregnancy) are treated with diet, exercise and/or medication. Managing blood sugar reduces risk for the mother and the baby. The glycemic index (GI) is a way of ranking the ability of food to raise blood sugar after eating. Recommending low GI foods may improve treatment of gestational diabetes, but has not been tested in this population. The main objective of this study is to see if using low GI food will result in better blood sugar 2 hours after meals. Blood sugar before breakfast, medication dose, inflammation and stress, complications of pregnancy, and maternal diabetes risk after pregnancy will be measured. Infant growth and mother's weight change post delivery will be measured. Information on participants' opinion of low GI will be collected. Women with gestational diabetes who volunteer will receive usual treatment, but will also be randomly assigned (like flipping a coin) to follow regular treatment or add low GI foods. Most study outcomes will be taken from participants' medical chart. In addition, diet records and questionnaires will be collected when the study starts, 4 weeks after the study starts, and 8 weeks and 1 year after delivery. An extra tube will be collected during regular blood work to measure inflammation and stress and if genetic makeup effects how the GI works. Results may help improve treatment of gestational diabetes. This study will collect information on perception of low GI food and how it affects blood sugar control.
Program
Operating Grant
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
225178
Name
Wolever Thomas M
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Clinical
Prcname2
Nutrition, Food & Health
Projecttitle
The effect of a low glycemic index (GI) diet on maternal glycemic control and maternal and neonatal markers of postpartum diabetes risk in women with gestational hyperglycemia.
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$444,989
Cihrequipment2
$0
Programname2
Operating Grant
Keyworddelim
Clinical Trial; Dietary Carbohydrates; Gestational Diabetes; Glycemic Control; Glycemic Index; Humans
Abstract
Women who develop gestational diabetes (high blood sugar during pregnancy) are treated with diet, exercise and/or medication. Managing blood sugar reduces risk for the mother and the baby. The glycemic index (GI) is a way of ranking the ability of food to raise blood sugar after eating. Recommending low GI foods may improve treatment of gestational diabetes, but has not been tested in this population. The main objective of this study is to see if using low GI food will result in better blood sugar 2 hours after meals. Blood sugar before breakfast, medication dose, inflammation and stress, complications of pregnancy, and maternal diabetes risk after pregnancy will be measured. Infant growth and mother's weight change post delivery will be measured. Information on participants' opinion of low GI will be collected. Women with gestational diabetes who volunteer will receive usual treatment, but will also be randomly assigned (like flipping a coin) to follow regular treatment or add low GI foods. Most study outcomes will be taken from participants' medical chart. In addition, diet records and questionnaires will be collected when the study starts, 4 weeks after the study starts, and 8 weeks and 1 year after delivery. An extra tube will be collected during regular blood work to measure inflammation and stress and if genetic makeup effects how the GI works. Results may help improve treatment of gestational diabetes. This study will collect information on perception of low GI food and how it affects blood sugar control.
Competitiondate
201103
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Wolever, Thomas M
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $444,989~ $0~