Grant: Project Grant

Anxiety and depression are among the most common and costly forms of disease and injury worldwide. Despite their enormous public health impact, treatments for these disorders are only moderately effective. A better understanding of pathways to anxiety and depression would be helpful in designing more effective interventions. This project will recruit a large sample of early adolescents-- a vulnerable population-- and will carefully measure self-report, behavioral, and neural measures of threat and reward sensitivity, as well as stress, to clarify pathways to anxiety and depression during this sensitive period.