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Grant: Project Grant

Unity Health Toronto

$374,850.00

Efficacy of Intermittent Superficial Parasternal Intercostal Plane Block on Postoperative Pain Control in Patients Undergoing Cardiac Surgery with Median Sternotomy

FY 2024-25

Summary
Many patients who undergo heart surgery experience long-term pain that if left unmanaged, can significantly reduce their quality of life, intensify their medical problems and increase their risk of dying. Identifying treatments to decrease the pain experienced after heart surgery and reduce the use of pain medicines called opioids is an important clinical priority. The superficial parasternal intercostal plane (SPIP) block is a procedure that involves administering a drug that reduces the feeling of pain between the chest wall muscle and the muscles between the ribs. There is currently very little data on the effectiveness of the SPIP to reduce pain and how it may affect the short- and long-term need for pain medications. The cross-Canada Enhanced PeriOperative Cardiovascular Healthcare (EPOCH) CardioLink-10 trial will involve roughly 314 participants who are undergoing heart surgery. It will investigate whether the pain medication ropivacaine improves pain control and pain-related outcomes among people who have undergone heart surgery that involved the separation of their breastbone. Assessments of pain, recovery, mental state (confusion), and need for pain medications will be assessed before discharge from the hospital as well as 6 weeks and 3 months after the surgery. EPOCH CardioLink-10 is one of the largest multicentre trial to date to evaluate a pain management strategy among heart surgery patients and will provide important information on how to manage pain and improve the quality of life these individuals.
Program
Project Grant
Location
Ontario, Canada
Recipient Type
Other
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
522679
Name
Mazer David
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Clinical
Prcname2
Clinical Investigation - D: Cardiovascular Systems
Projecttitle
Efficacy of Intermittent Superficial Parasternal Intercostal Plane Block on Postoperative Pain Control in Patients Undergoing Cardiac Surgery with Median Sternotomy
Programtype2
Operating Grants
Orgnameinp2
Unity Health Toronto
Cihramount2
$374,850
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Opioids, Cardiac Surgery, Pain, Perioperative Analgesia
Abstract
Many patients who undergo heart surgery experience long-term pain that if left unmanaged, can significantly reduce their quality of life, intensify their medical problems and increase their risk of dying. Identifying treatments to decrease the pain experienced after heart surgery and reduce the use of pain medicines called opioids is an important clinical priority. The superficial parasternal intercostal plane (SPIP) block is a procedure that involves administering a drug that reduces the feeling of pain between the chest wall muscle and the muscles between the ribs. There is currently very little data on the effectiveness of the SPIP to reduce pain and how it may affect the short- and long-term need for pain medications. The cross-Canada Enhanced PeriOperative Cardiovascular Healthcare (EPOCH) CardioLink-10 trial will involve roughly 314 participants who are undergoing heart surgery. It will investigate whether the pain medication ropivacaine improves pain control and pain-related outcomes among people who have undergone heart surgery that involved the separation of their breastbone. Assessments of pain, recovery, mental state (confusion), and need for pain medications will be assessed before discharge from the hospital as well as 6 weeks and 3 months after the surgery. EPOCH CardioLink-10 is one of the largest multicentre trial to date to evaluate a pain management strategy among heart surgery patients and will provide important information on how to manage pain and improve the quality of life these individuals.
Competitiondate
202503
Approvedterm2
3 yrs 0 mth
Pinamesdelim
Mazer, David; Verma, Subodh S
Approvedterm
3 ans 0 mois
Cihrcontribution2
~ $374,850~ $0~
Unity Health Toronto - $374,850 Grant (2024-25) | Canada Spends