Grant: Canada Research Chairs
The University of British Columbia
$200,000.00
Microbial catabolism and biocatalysis
FY 2023-24
Summary
Dr. Eltis¿s research has made major advances in understanding and harnessing the bacterial degradation of steroids and aromatic compounds, including lignin. This degradation is essential to the global carbon cycle and the health of the biosphere. Eltis is harnessing bacterial degradation activities to develop biocatalysts for sustainable industrial processes. In Mycobacterium tuberculosis, he has helped identify cholesterol degradation as a drug target. Eltis¿s research will continue to: provide paradigm-shifting insights into bacterial degradation and the enzymes involved; develop urgently needed novel therapeutics for treating tuberculosis; and engineer biocatalysts and platforms to transform forest biomass into high-value products.
Program
Canada Research Chairs
Recipient
Location
British Columbia, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
CRC-2020-00203
Name nom
Eltis, Lindsay
Department département
Microbiology and Immunology - The University of British Columbia
Organization id
2
Institution établissement
The University of British Columbia
Province en
British Columbia
Province fr
Colombie-Britannique
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2023
Competition year année de concours
2020
Award amount
200000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
10000
Research subject group en
The field of research available
Research subject group fr
The field of research available
Research subject en
Le domaine de recherche disponible
Research subject fr
Le domaine de recherche disponible
Field of research list codes
RDF10601;RDF10606
Field of research list names en
Biochemistry;Genetics
Field of research list names fr
Biochimie;Génétique
Application title
Microbial catabolism and biocatalysis
Keyword
bacteria
catabolism
enzyme
biocatalysis
steroid
lignin
tuberculosis
therapeutics
dioxygenase
C-C bond hydrolases
aromatic compound
degradation
actinobacteria
cholesterol
bacterial physiology
biomass
forestry products
Application summary
Dr. Eltis¿s research has made major advances in understanding and harnessing the bacterial degradation of steroids and aromatic compounds, including lignin. This degradation is essential to the global carbon cycle and the health of the biosphere. Eltis is harnessing bacterial degradation activities to develop biocatalysts for sustainable industrial processes. In Mycobacterium tuberculosis, he has helped identify cholesterol degradation as a drug target. Eltis¿s research will continue to: provide paradigm-shifting insights into bacterial degradation and the enzymes involved; develop urgently needed novel therapeutics for treating tuberculosis; and engineer biocatalysts and platforms to transform forest biomass into high-value products.
