Grant: CIHR-ICRH Travel Awards - ICRH / Vascular pool
Université Laval
$1,405.00
Association of D-dimers with Left Ventricular Hypertrophy and Clinical Outcomes in Mild to Moderate Aortic Stenosis: Results from the PROGRESSA Study
FY 2023-24
Summary
146 patients with mild or moderate aortic stenosis were included in this sub-analysis. Clinical and Doppler echocardiographic data were collected yearly over a period of 10 years. D-dimers levels were significantly associated with Left Ventricular hypertrophy. Over a median follow-up of 8.10 (5.57-9.94) years, 38 (26%) patients died. Higher D-dimer levels were associated with increased risk of all-cause mortality.The simple measure of this new blood biomarker could help to enhance risk stratification and optimize the timing of intervention in asymptomatic patients with aortic stenosis.
Department
Program
CIHR-ICRH Travel Awards - ICRH / Vascular pool
Recipient
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
495409
Name
Abdoun Kathia
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Prcname2
Special Cases
Projecttitle
Association of D-dimers with Left Ventricular Hypertrophy and Clinical Outcomes in Mild to Moderate Aortic Stenosis: Results from the PROGRESSA Study
Programtype2
Undefined
Orgnameinp2
Université Laval
Cihramount2
$1,405
Cihrequipment2
$0
Programname2
CIHR-ICRH Travel Awards - ICRH / Vascular pool
Keyworddelim
Aortic Stenosis; D-Dimers; Left Ventricular Hypertrophy
Abstract
146 patients with mild or moderate aortic stenosis were included in this sub-analysis. Clinical and Doppler echocardiographic data were collected yearly over a period of 10 years. D-dimers levels were significantly associated with Left Ventricular hypertrophy. Over a median follow-up of 8.10 (5.57-9.94) years, 38 (26%) patients died. Higher D-dimer levels were associated with increased risk of all-cause mortality.The simple measure of this new blood biomarker could help to enhance risk stratification and optimize the timing of intervention in asymptomatic patients with aortic stenosis.
Competitiondate
202309
Approvedterm2
1 yr 0 mth
Pinamesdelim
Abdoun, Kathia
Approvedterm
1 an 0 mois
Cihrcontribution2
~ $1,405~ $0~
