Grant: Travel Awards - Institute Community Support
Direct Payment
$500.00
Protein changes associated with a loss of smooth muscle alpha actin expression in vascular and non-vascular tissues of adult mice.
FY 2012-13
Summary
Defects in an important structural protein called smooth muscle alpha actin (SMAA) as a result of a gene mutation causes various diseases in humans. Relatively little is known about the effect of defective SMAA on the aorta, bladder, and colon, which are tissues that normally express high levels of this protein. Using a mice model lacking SMAA, I intend to study how these tissues respond through changes in protein expression. The results may shed light on how the various pathological states develop due to non-functional SMAA and provide targets for future research and therapies.
Department
Program
Travel Awards - Institute Community Support
Recipient
Location
Ontario, Canada
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
278611
Name
Wang Yuxiang
Region
Ontario
Country
Canada
Orgtype
Research Institution
Instname2
Circulatory and Respiratory Health
Theme2
Biomedical
Prcname2
Institute of Circulatory and Respiratory Health
Projecttitle
Protein changes associated with a loss of smooth muscle alpha actin expression in vascular and non-vascular tissues of adult mice.
Programtype2
Undefined
Orgnameinp2
Direct Payment
Cihramount2
$500
Cihrequipment2
$0
Programname2
Travel Awards - Institute Community Support
Keyworddelim
Actin; Aorta; Bladder; Colon; Fluorescence; Proteomics
Abstract
Defects in an important structural protein called smooth muscle alpha actin (SMAA) as a result of a gene mutation causes various diseases in humans. Relatively little is known about the effect of defective SMAA on the aorta, bladder, and colon, which are tissues that normally express high levels of this protein. Using a mice model lacking SMAA, I intend to study how these tissues respond through changes in protein expression. The results may shed light on how the various pathological states develop due to non-functional SMAA and provide targets for future research and therapies.
Competitiondate
201301
Approvedterm2
0 yr 3 mths
Pinamesdelim
Wang, Yuxiang
Approvedterm
0 an 3 mois
Cihrcontribution2
Inst of Circ &Respiratory Hlth~ $500~ $0~
