Grant: Project Grant

Stress is unavoidable, and if left unchecked can lead to various stress-related disorders, including anxiety disorders and depression. The current pandemic has seen a dramatic increase in stress-related disorders, likely due to the perceived helplessness individuals have experienced. It has also, however, led to increased social isolation. There is strong evidence that social interactions are critical for buffering the effects of stress. How this happens is not known. Here we seek to understand the brain mechanisms by which social touch buffers stress. By targeting specific cellular signals, our goal is to unveil therapeutic targets for the treatment of acute stress, and its related disorders.