Grant: Research Tools and Instruments
Brock University
$50,499.00
Electrophysiological recording equipment for the study of neural networks during memory formation
FY 2017-18
Summary
The equipment I am requesting is for an electrophysiological recording rig. The electrophysiological recordings we perform are electrical recordings from brain cells, which are used to measure the activity levels of cells, the flow of electrical current through specific membrane ion channels, and to measure the communication between different brain cells in a neural network. The research we are conducting aims to determine the role of the Vitamin A metabolite, retinoic acid, on memory formation. Blocking retinoic acid signaling pathways impedes memory formation in species from molluscs to humans. However, very little is known about how retinoic acid affects synaptic connections within networks of the brain. The equipment I have requested is essential recording equipment required to upgrade an electrophysiological recording rig to allow me to continue with my NSERC-funded research. A large component of my NSERC research is to investigate how retinoic acid contributes to memory formation, and specifically the changes that occur during the neural networks during behavioural changes.
Program
Research Tools and Instruments
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
RTI-2018-00375
Name nom
Spencer, Gaynor
Department département
Biological Sciences - Biological Sciences
Organization id
22
Institution établissement
Brock University
Province en
Ontario
Province fr
Ontario
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2017
Competition year année de concours
2018
Award amount
50499
Program id
RTI
Program name en
Research Tools and Instruments
Program name fr
Outils et instruments de recherche
Group en
Discovery grants programs
Group fr
Programmes de subventions à la découverte
Committee code
1601
Committee name en
Genes, Cells and Molecules (RTI)
Committee name fr
Gènes, cellules et molécules (OIR)
Area of application code
1200
Area of application group en
Advancement of knowledge
Area of application group fr
Avancement des connaissances
Area of application en
Advancement of knowledge
Area of application fr
Avancement des connaissances
Research subject code
5112
Research subject group en
Cell biology
Research subject group fr
Biologie cellulaire
Research subject en
Electrophysiology
Research subject fr
Électrophysiologie
Partie
1
Nb partie
1
Application title
Electrophysiological recording equipment for the study of neural networks during memory formation
Keyword
NSERC
Application summary
The equipment I am requesting is for an electrophysiological recording rig. The electrophysiological recordings we perform are electrical recordings from brain cells, which are used to measure the activity levels of cells, the flow of electrical current through specific membrane ion channels, and to measure the communication between different brain cells in a neural network. The research we are conducting aims to determine the role of the Vitamin A metabolite, retinoic acid, on memory formation. Blocking retinoic acid signaling pathways impedes memory formation in species from molluscs to humans. However, very little is known about how retinoic acid affects synaptic connections within networks of the brain. The equipment I have requested is essential recording equipment required to upgrade an electrophysiological recording rig to allow me to continue with my NSERC-funded research. A large component of my NSERC research is to investigate how retinoic acid contributes to memory formation, and specifically the changes that occur during the neural networks during behavioural changes.
