Grant: Project Grant
University of Toronto
$1,231,650.00
Exploring genetic network dynamics in the context of diverse genetic backgrounds
FY 2021-22
Summary
The heritability of complex traits, including disease, is governed by a complex interplay of many genetic variants. This project will produce unique datasets and tools that will reveal how groups of genes interact with each other and how networks of genetic interactions are rewired in response to different genetic backgrounds. The project will help us understand the link between genotype (the genetic code unique to a cell or organism) and phenotype (the traits or features of a cell or organism), a key frontier in genetics.
Department
Program
Project Grant
Recipient
Location
Ontario, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
462595
Name
Andrews Brenda J
Region
Ontario
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Genetics
Theme2
Biomedical
Prcname2
Genomics: Systems and computational biology
Projecttitle
Exploring genetic network dynamics in the context of diverse genetic backgrounds
Programtype2
Operating Grants
Orgnameinp2
University of Toronto
Cihramount2
$1,231,650
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Complex Genetics; Functional Genomics; Genetic Interactions; Genetic Suppressors; Missing Heritability; Yeast Genetics
Abstract
The heritability of complex traits, including disease, is governed by a complex interplay of many genetic variants. This project will produce unique datasets and tools that will reveal how groups of genes interact with each other and how networks of genetic interactions are rewired in response to different genetic backgrounds. The project will help us understand the link between genotype (the genetic code unique to a cell or organism) and phenotype (the traits or features of a cell or organism), a key frontier in genetics.
Competitiondate
202203
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Andrews, Brenda J
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $1,231,650~ $0~
