Grant: Canada Research Chairs
University of Manitoba
$200,000.00
Bioactive peptides
FY 2023-24
Summary
Food protein fragments obtained through enzyme digestion can be used as nutritional intervention tools that promote normal functioning of the human body and are called bioactive peptides. The functional performance and utility of bioactive peptides depend on the type and arrangement of natural amino acids on the chain. However, this critical information is missing and therefore, the proposed research program will elucidate how the chain arrangement of amino acids affect potency of peptides against proteins that play critical roles in maintaining normal body functions. The outcome of the research will provide new peptide tools for improved human nutrition.
Program
Canada Research Chairs
Recipient
Location
Manitoba, Canada
Recipient Type
Academia
Type
Grant
Source
NSERC's Awards Data
As published
Application id
CRC-2020-00290
Name nom
Aluko, Rotimi
Department département
Food and Human Nutritional Sciences - University of Manitoba
Organization id
19
Institution établissement
University of Manitoba
Province en
Manitoba
Province fr
Manitoba
Country en
CANADA
Country fr
CANADA
Fiscal year exercice financier
2023
Competition year année de concours
2020
Award amount
200000
Program id
CRC
Program name en
Canada Research Chairs
Program name fr
Chaires de recherche du Canada
Group en
DISCOVERY RESEARCH
Group fr
RECHERCHE AXÉE SUR LA DÉCOUVERTE
Committee code
9998
Committee name en
Canada Research Chair Selection Committee
Committee name fr
Comité de sélection des Chaires de recherche du Canada
Area of application code
9999
Area of application group en
Not available
Area of application group fr
Non disponible
Area of application en
Not available
Area of application fr
Non disponible
Research subject code
10000
Research subject group en
The field of research available
Research subject group fr
The field of research available
Research subject en
Le domaine de recherche disponible
Research subject fr
Le domaine de recherche disponible
Field of research list codes
RDF3030107;RDF40402
Field of research list names en
Nutrition and metabolism;Food sciences (including food engineering)
Field of research list names fr
Nutrition et métabolisme;Sciences de l'alimentation (y compris le génie de l'alimentation)
Application title
Bioactive peptides
Keyword
Bioactive peptides
Food proteins
Enzyme digestion
Protein hydrolysates
Membrane ultrafiltration
Amino acid sequencing
Peptide-ligand interactions
Human digestive enzymes
Human bitter taste receptors
Enzyme inhibition kinetics
Homeostasis
Rat feeding experiments
Application summary
Food protein fragments obtained through enzyme digestion can be used as nutritional intervention tools that promote normal functioning of the human body and are called bioactive peptides. The functional performance and utility of bioactive peptides depend on the type and arrangement of natural amino acids on the chain. However, this critical information is missing and therefore, the proposed research program will elucidate how the chain arrangement of amino acids affect potency of peptides against proteins that play critical roles in maintaining normal body functions. The outcome of the research will provide new peptide tools for improved human nutrition.
