Grant: Project Grant
Centre hospitalier de l'Université de Montréal (CHUM)
$845,325.00
UNDERSTANDING G3BP1 AND STRESS GRANULE DYNAMICS IN ALS PATHOGENESIS
FY 2019-20
Summary
ALS, also known as Lou Gehrig's disease, is a devastatingly fatal neurodegenerative disease. The death of specialized cells, called motor neurons, which control all voluntary movement, are why patients become paralyzed, unable to walk, talk, or eat. We are interested in how the cells affected in this disease combination deal with adverse conditions (environmental stress). Understanding the cell biology of this disease will open the door to better therapeutics and biomarkers.
Department
Program
Project Grant
Location
Quebec, Canada
Recipient Type
Not-for-profit organization or charity
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
408332
Name
Vande Velde Christine Diane C
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Neurosciences, Mental Health and Addiction
Theme2
Biomedical
Prcname2
Cell Biology - Disease
Projecttitle
UNDERSTANDING G3BP1 AND STRESS GRANULE DYNAMICS IN ALS PATHOGENESIS
Programtype2
Operating Grants
Orgnameinp2
Centre hospitalier de l'Université de Montréal (CHUM)
Cihramount2
$845,325
Cihrequipment2
$0
Programname2
Project Grant
Keyworddelim
Amyotrophic Lateral Sclerosis; Cell Biology; Environmental Stress; Neurodegeneration; Polyadenylation; Proteomics; Rna Binding Proteins; Rna Metabolism; Rna Stability; Stress Granules
Abstract
ALS, also known as Lou Gehrig's disease, is a devastatingly fatal neurodegenerative disease. The death of specialized cells, called motor neurons, which control all voluntary movement, are why patients become paralyzed, unable to walk, talk, or eat. We are interested in how the cells affected in this disease combination deal with adverse conditions (environmental stress). Understanding the cell biology of this disease will open the door to better therapeutics and biomarkers.
Competitiondate
201909
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Vande Velde, Christine Diane C
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $845,325~ $0~
