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Grant: Travel Awards - Institute Community Support

Memorial University of Newfoundland

$2,500.00

Life in plastic: Effects of polystyrene nanoplastic exposure on maternal caretaking behaviour, litter sex ratio, and offspring growth in two laboratory mouse strains

FY 2025-26

Summary
Plastic waste in oceans and landfills breaks down into tiny particles called microplastics and nanoplastics, which can enter animals' bodies and disrupt hormones important for growth and reproduction. Most studies focus on adult males, leaving gaps in understanding how early-life exposure affects females or developing offspring. Our research explores how exposure to nanoplastics during pregnancy influences maternal behaviour and pup development in mice. Pregnant mice were given either normal water or water containing a low dose of polystyrene nanoplastics from early pregnancy to 10 days after birth. We then observed maternal care behaviors like nursing and grooming, along with pup growth and sex ratios. Early findings show that pups born to exposed mothers weigh less than controls, suggesting that nanoplastic exposure may alter maternal care and, in turn, offspring development.
Program
Travel Awards - Institute Community Support
Location
Newfoundland and Labrador, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database

As published

Id
559021
Name
Fowler Lucas F
Region
Newfoundland and Labrador
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Gender and Health
Theme2
Biomedical
Prcname2
Travel Awards - Institute Community Support
Projecttitle
Life in plastic: Effects of polystyrene nanoplastic exposure on maternal caretaking behaviour, litter sex ratio, and offspring growth in two laboratory mouse strains
Programtype2
Undefined
Orgnameinp2
Memorial University of Newfoundland
Cihramount2
$2,500
Cihrequipment2
$0
Programname2
Travel Awards - Institute Community Support
Keyworddelim
Development; Ics Travel Awards; Maternity; Micro/Nanoplastic Exposure; Sex Differences
Abstract
Plastic waste in oceans and landfills breaks down into tiny particles called microplastics and nanoplastics, which can enter animals' bodies and disrupt hormones important for growth and reproduction. Most studies focus on adult males, leaving gaps in understanding how early-life exposure affects females or developing offspring. Our research explores how exposure to nanoplastics during pregnancy influences maternal behaviour and pup development in mice. Pregnant mice were given either normal water or water containing a low dose of polystyrene nanoplastics from early pregnancy to 10 days after birth. We then observed maternal care behaviors like nursing and grooming, along with pup growth and sex ratios. Early findings show that pups born to exposed mothers weigh less than controls, suggesting that nanoplastic exposure may alter maternal care and, in turn, offspring development.
Competitiondate
202511
Approvedterm2
1 yr 0 mth
Pinamesdelim
Fowler, Lucas F
Approvedterm
1 an 0 mois
Cihrcontribution2
IGH~ $2,500~ $0~
Memorial University of Newfoundland - $2,500 Grant (2… | Canada Spends