Grant: CIHR Fellowship

Stroke is the number one cause of neurological disability in Canada and the second most common cause of dementia. However, current rehabilitation standards do not adequately address the cognitive consequences of stroke (e.g., memory disorders and impaired reasoning). First, much of the focus in stroke rehabilitation is on physical recovery. Second, rarely does rehabilitation continue past 12 months post-stroke due to the belief that stroke survivors have reached their maximum potential for recovery by this time. Yet up to 30% of stroke survivors develop cognitive impairment and dementia 12 months post-stroke. Such consequences of stroke are thus not addressed by our current model of rehabilitation. Research suggests exercise training is a promising strategy to promote cognitive function. However, stroke survivors often have physical impairments that limit their ability to exercise. We propose participating in social activities, which are less physically demanding but intellectually stimulating, is an effective alternative to exercise for promoting cognitive function. The proposed study aims to evaluate the individual effect of two distinct treatments - an exercise training program and a cognitive and social enrichment program - on cognitive function in stroke survivors. Secondly, the study will evaluate how these two treatments may improve cognitive function. Specifically, we will look at improved sleep as an important pathway. Our findings will contribute to development of effective community programs to help stroke survivors. We aim to impact their quality of life through improved cognitive function and increased ability to participate in social and leisure activities. Our research targets three key advances: 1) an improved standard of care for stroke survivors; 2) new treatments to promote cognitive function and thereby increase quality of post-stroke life; and 3) a better understanding of how these treatments work so we can refine them for greater effectiveness.