Grant: CIHR New Investigator
Université Laval
$300,000.00
Endobiotics glucuronidation: a novel therapeutic avenue for metabolic and endocrine diseases
FY 2008-09
Summary
Glucuronidation is an enzymatic reaction very well studied for the role its plays in drug elimination. However, this reaction also affects a wide variety of endogenous substance. The aim of our research program is to determine whether controlling the elimination of specific endogenous compounds through the use of novel drugs can be of therapeutic value in the treatment of various pathologies such as liver diseases, cardiovascular diseases or prostate cancer.
Department
Program
CIHR New Investigator
Recipient
Location
Quebec, Canada
Recipient Type
Academia
Type
Grant
Source
CIHR Funding Decisions Database
As published
Id
172371
Name
Barbier Olivier
Region
Québec
Country
Canada
Orgtype
Institution Paid; Research Institution
Instname2
Nutrition, Metabolism and Diabetes
Theme2
Biomedical
Prcname2
New Investigators C
Projecttitle
Endobiotics glucuronidation: a novel therapeutic avenue for metabolic and endocrine diseases
Programtype2
Salary Programs
Orgnameinp2
Université Laval
Cihramount2
$300,000
Cihrequipment2
$0
Programname2
CIHR New Investigator
Keyworddelim
Cardiovascular Diseases; Endobiotics Metabolism; Gene Regulation; Hormonal Diseases; Liver Diseases; Molecular Pharmacology
Abstract
Glucuronidation is an enzymatic reaction very well studied for the role its plays in drug elimination. However, this reaction also affects a wide variety of endogenous substance. The aim of our research program is to determine whether controlling the elimination of specific endogenous compounds through the use of novel drugs can be of therapeutic value in the treatment of various pathologies such as liver diseases, cardiovascular diseases or prostate cancer.
Competitiondate
200809
Approvedterm2
5 yrs 0 mth
Pinamesdelim
Barbier, Olivier
Approvedterm
5 ans 0 mois
Cihrcontribution2
~ $300,000~ $0~
